| Starters | ||
| Pos | Player | Points |
| QB | Carson Wentz QB | 5.30 |
| RB | Derrick Henry RB | 22.20 |
| RB | Austin Ekeler RB | 31.90 |
| WR | Allen Lazard WR | 14.60 |
| WR | Devin Duvernay WR | 9.10 |
| WR | Garrett Wilson WR | 5.10 |
| TE | Travis Kelce TE | 19.70 |
| FLEX | Jamaal Williams RB | 23.40 |
| FLEX | Cam Akers RB | 1.30 |
| DST | Los Angeles Chargers DST | 8.00 |
| Total | 140.6 | |
| Starters | ||
| Pos | Player | Points |
| QB | Kyler Murray QB | 24.88 |
| RB | Aaron Jones RB | 13.00 |
| RB | Kenneth Walker RB | 2.90 |
| WR | Nelson Agholor WR | 6.10 |
| WR | Mike Evans WR | 26.30 |
| WR | Christian Kirk WR | 7.30 |
| TE | Cole Kmet TE | 3.10 |
| FLEX | Michael Carter RB | 3.90 |
| FLEX | Dameon Pierce RB | 22.90 |
| DST | Kansas City Chiefs DST | 3.00 |
| Total | 113.38 | |
| Bench | ||
| Pos | Player | Points |
| BN | Arizona Cardinals DST | 13.00 |
| BN | Chase Edmonds RB | 9.00 |
| BN | Dallas Goedert TE | 9.70 |
| BN | Russell Gage WR | 3.40 |
| BN | Taysom Hill TE | 8.10 |
| BN | Mecole Hardman WR | 0.90 |
| BN | Amon-Ra St. Brown WR | 0.00 |
| BN | Skyy Moore WR | 4.70 |
| BN | Brian Robinson RB | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Josh Gordon WR | 0.00 |
| BN | Tevin Coleman RB | 0.00 |
| BN | Odell Beckham WR | 0.00 |
| BN | Jameis Winston QB | 0.00 |
| BN | New England Patriots DST | 8.00 |
| BN | O.J. Howard TE | 3.70 |
| BN | Jonnu Smith TE | 0.00 |
| BN | Sony Michel RB | 4.20 |
| BN | K.J. Hamler WR | 6.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Ryan Tannehill QB | 18.38 | 28.8% |
| RB | Austin Ekeler RB | 31.90 | 97.8% |
| RB | Jamaal Williams RB | 23.40 | |
| WR | Jamal Agnew WR | 22.90 | 76.8% |
| WR | Allen Lazard WR | 14.60 | |
| TE | Travis Kelce TE | 19.70 | 100% |
| FLEX | Derrick Henry RB | 22.20 | 77.4% |
| FLEX | Dallas Goedert TE | 9.70 | |
| DST | Arizona Cardinals DST | 13.00 | 61.5% |
| Total | 175.78 | 80% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Kyler Murray QB | 24.88 | 100% |
| RB | Dameon Pierce RB | 22.90 | 44.3% |
| RB | Aaron Jones RB | 13.00 | |
| WR | Mike Evans WR | 26.30 | 118.2% |
| WR | Christian Kirk WR | 7.30 | |
| TE | Trey McBride TE | 3.90 | 79.5% |
| FLEX | Nelson Agholor WR | 6.10 | 221.5% |
| FLEX | K.J. Hamler WR | 6.00 | |
| DST | New England Patriots DST | 8.00 | 37.5% |
| Total | 118.38 | 95.8% | |