| Starters | ||
| Pos | Player | Points |
| QB | Kyler Murray QB | 12.88 |
| RB | Aaron Jones RB | 5.90 |
| RB | Kenneth Walker RB | 18.00 |
| WR | Nelson Agholor WR | 0.00 |
| WR | Mike Evans WR | 6.20 |
| WR | Christian Kirk WR | 8.80 |
| TE | Cole Kmet TE | 2.00 |
| FLEX | K.J. Hamler WR | 5.40 |
| FLEX | Michael Carter RB | 5.20 |
| DST | New England Patriots DST | 13.00 |
| Total | 77.38 | |
| Starters | ||
| Pos | Player | Points |
| QB | Russell Wilson QB | 15.82 |
| RB | David Montgomery RB | 8.50 |
| RB | Travis Etienne RB | 11.80 |
| WR | Hollywood Brown WR | 9.30 |
| WR | Justin Jefferson WR | 13.70 |
| WR | DeVonta Smith WR | 12.90 |
| TE | Hunter Henry TE | 14.10 |
| FLEX | Braxton Berrios WR | 12.25 |
| FLEX | Jonathan Taylor RB | 0.00 |
| DST | San Francisco 49ers DST | 4.00 |
| Total | 102.37 | |
| Bench | ||
| Pos | Player | Points |
| BN | Josh Gordon WR | 0.00 |
| BN | Tevin Coleman RB | 0.30 |
| BN | Odell Beckham WR | 0.00 |
| BN | Jameis Winston QB | 0.00 |
| BN | Kansas City Chiefs DST | 0.00 |
| BN | O.J. Howard TE | 0.00 |
| BN | Jonnu Smith TE | 7.10 |
| BN | Sony Michel RB | 5.70 |
| BN | Dameon Pierce RB | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Julio Jones WR | 0.00 |
| BN | Robert Woods WR | 0.00 |
| BN | Cole Beasley WR | 0.00 |
| BN | Green Bay Packers DST | 4.00 |
| BN | Cordarrelle Patterson RB | 0.00 |
| BN | DJ Chark Jr. WR | 0.00 |
| BN | Pat Freiermuth TE | 0.00 |
| BN | Justin Fields QB | 18.40 |
| BN | Kyle Trask QB | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Kyler Murray QB | 12.88 | 100% |
| RB | Kenneth Walker RB | 18.00 | 100% |
| RB | Aaron Jones RB | 5.90 | |
| WR | TreQuan Smith WR | 11.80 | 72.8% |
| WR | Christian Kirk WR | 8.80 | |
| TE | Jonnu Smith TE | 7.10 | 28.2% |
| FLEX | Mike Evans WR | 6.20 | 89.1% |
| FLEX | Sony Michel RB | 5.70 | |
| DST | New England Patriots DST | 13.00 | 100% |
| Total | 89.38 | 86.6% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Justin Fields QB | 18.40 | 86% |
| RB | Travis Etienne RB | 11.80 | 100% |
| RB | David Montgomery RB | 8.50 | |
| WR | Justin Jefferson WR | 13.70 | 135% |
| WR | DeVonta Smith WR | 12.90 | |
| TE | Hunter Henry TE | 14.10 | 100% |
| FLEX | Braxton Berrios WR | 12.25 | 56.8% |
| FLEX | Hollywood Brown WR | 9.30 | |
| DST | Green Bay Packers DST | 4.00 | 100% |
| Total | 104.95 | 97.5% | |