| Starters | ||
| Pos | Player | Points |
| QB | Justin Herbert QB | 6.42 |
| RB | Dalvin Cook RB | 14.80 |
| RB | Breece Hall RB | 19.10 |
| WR | Tyler Lockett WR | 2.70 |
| WR | JuJu Smith-Schuster WR | 19.80 |
| WR | Jerry Jeudy WR | 6.90 |
| TE | Kyle Pitts TE | 9.40 |
| FLEX | Melvin Gordon RB | 0.80 |
| FLEX | Clyde Edwards-Helaire RB | 3.30 |
| DST | Denver Broncos DST | 6.00 |
| Total | 89.22 | |
| Starters | ||
| Pos | Player | Points |
| QB | Geno Smith QB | 12.68 |
| RB | Austin Ekeler RB | 19.30 |
| RB | Cam Akers RB | 0.00 |
| WR | Allen Lazard WR | 15.60 |
| WR | Devin Duvernay WR | 2.50 |
| WR | Garrett Wilson WR | 1.30 |
| TE | Travis Kelce TE | 15.20 |
| FLEX | Dallas Goedert TE | 3.20 |
| FLEX | Taysom Hill TE | 4.54 |
| DST | Los Angeles Chargers DST | 9.00 |
| Total | 83.32 | |
| Bench | ||
| Pos | Player | Points |
| BN | A.J. Green WR | 1.70 |
| BN | Tyler Boyd WR | 9.60 |
| BN | Brandin Cooks WR | 0.00 |
| BN | Marlon Mack RB | 0.00 |
| BN | Quintez Cephus WR | 0.00 |
| BN | Zach Wilson QB | 4.50 |
| BN | Rachaad White RB | 6.50 |
| BN | David Bell WR | 1.80 |
| BN | Isaiah Spiller RB | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Arizona Cardinals DST | 15.00 |
| BN | Derrick Henry RB | 0.00 |
| BN | Carson Wentz QB | 4.16 |
| BN | Jamaal Williams RB | 0.00 |
| BN | Russell Gage WR | 3.00 |
| BN | Mecole Hardman WR | 12.20 |
| BN | Amon-Ra St. Brown WR | 0.00 |
| BN | Skyy Moore WR | 3.20 |
| BN | Brian Robinson RB | 12.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Justin Herbert QB | 6.42 | 100% |
| RB | Breece Hall RB | 19.10 | 100% |
| RB | Dalvin Cook RB | 14.80 | |
| WR | JuJu Smith-Schuster WR | 19.80 | 100% |
| WR | Tyler Boyd WR | 9.60 | |
| TE | Kyle Pitts TE | 9.40 | 100% |
| FLEX | Jerry Jeudy WR | 6.90 | 30.6% |
| FLEX | Rachaad White RB | 6.50 | |
| DST | Denver Broncos DST | 6.00 | 100% |
| Total | 98.52 | 90.6% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Geno Smith QB | 12.68 | 100% |
| RB | Austin Ekeler RB | 19.30 | 61.7% |
| RB | Brian Robinson RB | 12.00 | |
| WR | Allen Lazard WR | 15.60 | 69.8% |
| WR | Mecole Hardman WR | 12.20 | |
| TE | Travis Kelce TE | 15.20 | 100% |
| FLEX | Taysom Hill TE | 4.54 | 86.1% |
| FLEX | Jamal Agnew WR | 4.45 | |
| DST | Arizona Cardinals DST | 15.00 | 60% |
| Total | 110.97 | 75.1% | |