| Starters | ||
| Pos | Player | Points |
| QB | Justin Herbert QB | 12.10 |
| RB | Dalvin Cook RB | 12.60 |
| RB | DAndre Swift RB | 6.50 |
| WR | Tyler Boyd WR | 6.90 |
| WR | Tyler Lockett WR | 15.20 |
| WR | JuJu Smith-Schuster WR | 13.80 |
| TE | Kyle Pitts TE | 3.70 |
| FLEX | Kenyan Drake RB | 23.90 |
| FLEX | Clyde Edwards-Helaire RB | 2.40 |
| DST | New York Jets DST | 10.00 |
| Total | 107.1 | |
| Starters | ||
| Pos | Player | Points |
| QB | Patrick Mahomes QB | 34.14 |
| RB | Justice Hill RB | 2.85 |
| RB | Devin Singletary RB | 6.80 |
| WR | Tyreek Hill WR | 23.80 |
| WR | Chase Claypool WR | 2.70 |
| WR | Drake London WR | 1.80 |
| TE | Zach Ertz TE | 12.50 |
| FLEX | Mike Gesicki TE | 0.80 |
| FLEX | Tyquan Thornton WR | 1.00 |
| DST | Baltimore Ravens DST | 11.00 |
| Total | 97.39 | |
| Bench | ||
| Pos | Player | Points |
| BN | Denver Broncos DST | 0.00 |
| BN | Melvin Gordon RB | 0.00 |
| BN | Sammy Watkins WR | 1.40 |
| BN | Brandin Cooks WR | 0.00 |
| BN | Jerry Jeudy WR | 0.00 |
| BN | Zach Wilson QB | 12.56 |
| BN | Rachaad White RB | 6.15 |
| BN | David Bell WR | 0.00 |
| BN | Isaiah Spiller RB | 2.90 |
| Bench | ||
| Pos | Player | Points |
| BN | Chicago Bears DST | -4.00 |
| BN | Derek Carr QB | 22.36 |
| BN | Jarvis Landry WR | 0.00 |
| BN | J.D. McKissic RB | 0.00 |
| BN | J.K. Dobbins RB | 0.00 |
| BN | Najee Harris RB | 0.00 |
| BN | Rashod Bateman WR | 0.00 |
| BN | Jahan Dotson WR | 0.00 |
| BN | Jalen Tolbert WR | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Zach Wilson QB | 12.56 | 96.3% |
| RB | Kenyan Drake RB | 23.90 | 52.3% |
| RB | Dalvin Cook RB | 12.60 | |
| WR | Tyler Lockett WR | 15.20 | 123.8% |
| WR | JuJu Smith-Schuster WR | 13.80 | |
| TE | Kyle Pitts TE | 3.70 | 100% |
| FLEX | Tyler Boyd WR | 6.90 | 196.3% |
| FLEX | DAndre Swift RB | 6.50 | |
| DST | New York Jets DST | 10.00 | 100% |
| Total | 105.16 | 101.8% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Patrick Mahomes QB | 34.14 | 100% |
| RB | Devin Singletary RB | 6.80 | 100% |
| RB | Justice Hill RB | 2.85 | |
| WR | Tyreek Hill WR | 23.80 | 106.8% |
| WR | Chase Claypool WR | 2.70 | |
| TE | Zach Ertz TE | 12.50 | 100% |
| FLEX | Austin Hooper TE | 4.40 | 29% |
| FLEX | Drake London WR | 1.80 | |
| DST | Baltimore Ravens DST | 11.00 | 100% |
| Total | 99.99 | 97.4% | |