| Starters | ||
| Pos | Player | Points |
| QB | Tua Tagovailoa QB | 29.40 |
| RB | Alvin Kamara RB | 6.00 |
| RB | Saquon Barkley RB | 22.50 |
| WR | Chris Godwin WR | 16.10 |
| WR | A.J. Brown WR | 1.20 |
| WR | Gabriel Davis WR | 18.30 |
| TE | George Kittle TE | 2.60 |
| FLEX | Nick Chubb RB | 13.60 |
| FLEX | Khalil Herbert RB | 9.05 |
| DST | Los Angeles Rams DST | 4.00 |
| Total | 122.75 | |
| Starters | ||
| Pos | Player | Points |
| QB | Josh Allen QB | 17.60 |
| RB | Leonard Fournette RB | 8.30 |
| RB | Christian McCaffrey RB | 15.70 |
| WR | DeAndre Hopkins WR | 14.80 |
| WR | Amari Cooper WR | 4.70 |
| WR | Davante Adams WR | 23.10 |
| TE | Dalton Schultz TE | 14.40 |
| FLEX | DOnta Foreman RB | 19.00 |
| FLEX | Antonio Gibson RB | 14.00 |
| DST | Tampa Bay Buccaneers DST | 8.00 |
| Total | 139.6 | |
| Bench | ||
| Pos | Player | Points |
| BN | Pittsburgh Steelers DST | 12.00 |
| BN | Dak Prescott QB | 21.20 |
| BN | Marvin Jones WR | 3.80 |
| BN | Mike Williams WR | 0.00 |
| BN | Courtland Sutton WR | 9.60 |
| BN | Marquez Valdes-Scantling WR | 13.50 |
| BN | Robert Tonyan TE | 1.30 |
| BN | George Pickens WR | 13.00 |
| BN | Romeo Doubs WR | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Keenan Allen WR | 0.00 |
| BN | Cincinnati Bengals DST | 0.00 |
| BN | Kirk Cousins QB | 13.48 |
| BN | Tyler Higbee TE | 11.30 |
| BN | Joe Mixon RB | 0.00 |
| BN | Curtis Samuel WR | 5.00 |
| BN | Adam Thielen WR | 7.40 |
| BN | Raheem Mostert RB | 19.70 |
| BN | Nyheim Hines RB | 2.65 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Tua Tagovailoa QB | 29.40 | 100% |
| RB | Saquon Barkley RB | 22.50 | 78.9% |
| RB | Nick Chubb RB | 13.60 | |
| WR | Gabriel Davis WR | 18.30 | 103.5% |
| WR | Chris Godwin WR | 16.10 | |
| TE | George Kittle TE | 2.60 | 100% |
| FLEX | Marquez Valdes-Scantling WR | 13.50 | 85.5% |
| FLEX | George Pickens WR | 13.00 | |
| DST | Pittsburgh Steelers DST | 12.00 | 33.3% |
| Total | 141 | 87.1% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Marcus Mariota QB | 19.74 | 89.2% |
| RB | Raheem Mostert RB | 19.70 | 62% |
| RB | DOnta Foreman RB | 19.00 | |
| WR | Davante Adams WR | 23.10 | 112.4% |
| WR | DeAndre Hopkins WR | 14.80 | |
| TE | Dalton Schultz TE | 14.40 | 100% |
| FLEX | Christian McCaffrey RB | 15.70 | 111.1% |
| FLEX | Antonio Gibson RB | 14.00 | |
| DST | Tampa Bay Buccaneers DST | 8.00 | 100% |
| Total | 148.44 | 94% | |