| Starters | ||
| Pos | Player | Points |
| QB | Jalen Hurts QB | 26.20 |
| RB | Miles Sanders RB | 5.30 |
| RB | Rhamondre Stevenson RB | 11.20 |
| WR | Stefon Diggs WR | 12.80 |
| WR | Deebo Samuel WR | 18.90 |
| WR | Michael Pittman Jr. WR | 10.50 |
| TE | Mark Andrews TE | 9.30 |
| FLEX | Ezekiel Elliott RB | 17.20 |
| FLEX | Jakobi Meyers WR | 7.20 |
| DST | New Orleans Saints DST | 4.00 |
| Total | 122.6 | |
| Starters | ||
| Pos | Player | Points |
| QB | Justin Herbert QB | 21.20 |
| RB | Dalvin Cook RB | 7.20 |
| RB | DAndre Swift RB | 10.70 |
| WR | Tyler Boyd WR | 5.20 |
| WR | Brandin Cooks WR | 8.50 |
| WR | David Bell WR | 4.20 |
| TE | Kyle Pitts TE | 5.80 |
| FLEX | Melvin Gordon RB | 9.50 |
| FLEX | Kenyan Drake RB | 6.30 |
| DST | New York Jets DST | 11.00 |
| Total | 89.6 | |
| Bench | ||
| Pos | Player | Points |
| BN | Tom Brady QB | 0.00 |
| BN | Buffalo Bills DST | 4.00 |
| BN | David Njoku TE | 2.70 |
| BN | Calvin Ridley WR | 0.00 |
| BN | Jeff Wilson Jr. RB | 0.00 |
| BN | Gus Edwards RB | 0.00 |
| BN | Kenneth Gainwell RB | 0.00 |
| BN | Jaylen Warren RB | 1.40 |
| Bench | ||
| Pos | Player | Points |
| BN | Denver Broncos DST | -2.00 |
| BN | Tyler Lockett WR | 0.00 |
| BN | Sammy Watkins WR | 0.00 |
| BN | JuJu Smith-Schuster WR | 0.00 |
| BN | Jerry Jeudy WR | 0.00 |
| BN | Clyde Edwards-Helaire RB | 0.90 |
| BN | Zach Wilson QB | 5.68 |
| BN | Rachaad White RB | 0.00 |
| BN | Isaiah Spiller RB | 3.20 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Jalen Hurts QB | 26.20 | 100% |
| RB | Ezekiel Elliott RB | 17.20 | 58.1% |
| RB | Rhamondre Stevenson RB | 11.20 | |
| WR | Deebo Samuel WR | 18.90 | 133.1% |
| WR | Stefon Diggs WR | 12.80 | |
| TE | Mark Andrews TE | 9.30 | 100% |
| FLEX | Michael Pittman Jr. WR | 10.50 | 137.9% |
| FLEX | Jakobi Meyers WR | 7.20 | |
| DST | New Orleans Saints DST | 4.00 | 100% |
| Total | 117.3 | 104.5% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Justin Herbert QB | 21.20 | 100% |
| RB | DAndre Swift RB | 10.70 | 88.6% |
| RB | Melvin Gordon RB | 9.50 | |
| WR | Brandin Cooks WR | 8.50 | 107.2% |
| WR | Mack Hollins WR | 8.20 | |
| TE | Kyle Pitts TE | 5.80 | 100% |
| FLEX | A.J. Green WR | 7.50 | 107.5% |
| FLEX | Dalvin Cook RB | 7.20 | |
| DST | New York Jets DST | 11.00 | 100% |
| Total | 89.6 | 100% | |