| Starters | ||
| Pos | Player | Points |
| QB | Justin Herbert QB | 21.48 |
| RB | Dalvin Cook RB | 8.10 |
| RB | DAndre Swift RB | 5.40 |
| WR | Tyler Lockett WR | 14.50 |
| WR | JuJu Smith-Schuster WR | 17.90 |
| WR | Jerry Jeudy WR | 29.30 |
| TE | Tyler Conklin TE | 5.30 |
| FLEX | Tyler Boyd WR | 0.00 |
| FLEX | Rachaad White RB | 8.20 |
| DST | New York Jets DST | 9.00 |
| Total | 119.18 | |
| Starters | ||
| Pos | Player | Points |
| QB | Joe Burrow QB | 18.56 |
| RB | Tony Pollard RB | 20.20 |
| RB | Bam Knight RB | 14.70 |
| WR | Darius Slayton WR | 5.20 |
| WR | Jaylen Waddle WR | 4.10 |
| WR | Josh Palmer WR | 7.30 |
| TE | Evan Engram TE | 33.70 |
| FLEX | Kareem Hunt RB | 2.20 |
| FLEX | James Cook RB | 2.00 |
| DST | Dallas Cowboys DST | 4.00 |
| Total | 111.96 | |
| Bench | ||
| Pos | Player | Points |
| BN | Denver Broncos DST | 4.00 |
| BN | Melvin Gordon RB | 0.00 |
| BN | Kenyan Drake RB | 1.20 |
| BN | Brandin Cooks WR | 0.00 |
| BN | Clyde Edwards-Helaire RB | 0.00 |
| BN | Kyle Pitts TE | 0.00 |
| BN | Zach Wilson QB | 0.00 |
| BN | David Bell WR | 4.20 |
| BN | Isaiah Spiller RB | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Philadelphia Eagles DST | 9.00 |
| BN | Darren Waller TE | 0.00 |
| BN | Noah Fant TE | 0.00 |
| BN | Alexander Mattison RB | -0.10 |
| BN | A.J. Dillon RB | 0.00 |
| BN | Darnell Mooney WR | 0.00 |
| BN | Trevor Lawrence QB | 39.42 |
| BN | Terrace Marshall WR | 2.30 |
| BN | Rondale Moore WR | 0.00 |
| BN | Isaiah Likely TE | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Justin Herbert QB | 21.48 | 100% |
| RB | Marlon Mack RB | 14.70 | 59% |
| RB | Rachaad White RB | 8.20 | |
| WR | Jerry Jeudy WR | 29.30 | 130.7% |
| WR | JuJu Smith-Schuster WR | 17.90 | |
| TE | Tyler Conklin TE | 5.30 | 100% |
| FLEX | Tyler Lockett WR | 14.50 | 36.3% |
| FLEX | Dalvin Cook RB | 8.10 | |
| DST | New York Jets DST | 9.00 | 100% |
| Total | 128.48 | 92.8% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Trevor Lawrence QB | 39.42 | 47.1% |
| RB | Tony Pollard RB | 20.20 | 100% |
| RB | Bam Knight RB | 14.70 | |
| WR | Jameson Williams WR | 10.60 | 92.7% |
| WR | Josh Palmer WR | 7.30 | |
| TE | Evan Engram TE | 33.70 | 100% |
| FLEX | Darius Slayton WR | 5.20 | 45.2% |
| FLEX | Jaylen Waddle WR | 4.10 | |
| DST | Philadelphia Eagles DST | 9.00 | 44.4% |
| Total | 144.22 | 77.6% | |