| Starters | ||
| Pos | Player | Points |
| QB | Kyler Murray QB | 0.66 |
| RB | Sony Michel RB | 0.00 |
| RB | Michael Carter RB | 1.50 |
| WR | Nelson Agholor WR | 5.70 |
| WR | Josh Reynolds WR | 13.60 |
| WR | Christian Kirk WR | 7.00 |
| TE | Jonnu Smith TE | 0.00 |
| FLEX | Kenneth Walker RB | 0.00 |
| FLEX | Dameon Pierce RB | 11.80 |
| DST | New England Patriots DST | 19.00 |
| Total | 59.26 | |
| Starters | ||
| Pos | Player | Points |
| QB | Patrick Mahomes QB | 19.78 |
| RB | Alvin Kamara RB | 0.00 |
| RB | Devin Singletary RB | 4.80 |
| WR | Tyreek Hill WR | 22.10 |
| WR | Chris Godwin WR | 7.90 |
| WR | Gabriel Davis WR | 4.60 |
| TE | Dawson Knox TE | 12.10 |
| FLEX | Najee Harris RB | 12.00 |
| FLEX | Kyren Williams RB | 3.40 |
| DST | Baltimore Ravens DST | 11.00 |
| Total | 97.68 | |
| Bench | ||
| Pos | Player | Points |
| BN | Josh Gordon WR | 0.00 |
| BN | Odell Beckham WR | 0.00 |
| BN | Jameis Winston QB | 0.00 |
| BN | Kansas City Chiefs DST | 15.00 |
| BN | Jared Goff QB | 32.10 |
| BN | Aaron Jones RB | 0.00 |
| BN | O.J. Howard TE | 0.00 |
| BN | Cole Kmet TE | 0.00 |
| BN | K.J. Hamler WR | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Chicago Bears DST | 0.00 |
| BN | Derek Carr QB | -1.42 |
| BN | Jarvis Landry WR | 0.00 |
| BN | Mike Gesicki TE | 0.00 |
| BN | Chase Claypool WR | 0.00 |
| BN | Drake London WR | 0.00 |
| BN | Jahan Dotson WR | 0.00 |
| BN | Jalen Tolbert WR | 0.00 |
| BN | Tyquan Thornton WR | 4.80 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Jared Goff QB | 32.10 | 2.1% |
| RB | Dameon Pierce RB | 11.80 | 7.2% |
| RB | Samaje Perine RB | 8.90 | |
| WR | Josh Reynolds WR | 13.60 | 127.7% |
| WR | Christian Kirk WR | 7.00 | |
| TE | Trey McBride TE | 4.30 | 0% |
| FLEX | Nelson Agholor WR | 5.70 | 163.9% |
| FLEX | Michael Carter RB | 1.50 | |
| DST | New England Patriots DST | 19.00 | 100% |
| Total | 103.9 | 57% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Patrick Mahomes QB | 19.78 | 100% |
| RB | J.K. Dobbins RB | 18.00 | 16% |
| RB | Najee Harris RB | 12.00 | |
| WR | Tyreek Hill WR | 22.10 | 115.3% |
| WR | Chris Godwin WR | 7.90 | |
| TE | Dawson Knox TE | 12.10 | 100% |
| FLEX | Devin Singletary RB | 4.80 | 160.4% |
| FLEX | Tyquan Thornton WR | 4.80 | |
| DST | Baltimore Ravens DST | 11.00 | 100% |
| Total | 112.48 | 86.8% | |