| Starters | ||
| Pos | Player | Points |
| QB | Ben Roethlisberger QB | 17.90 |
| RB | Carlos Hyde RB | 11.40 |
| RB | Jordan Howard RB | 5.40 |
| WR | Jordan Matthews WR | 1.90 |
| WR | Tyler Lockett WR | 5.90 |
| TE | Cameron Brate TE | 1.50 |
| FLEX | Derrick Henry RB | 5.20 |
| FLEX | Theo Riddick RB | 12.20 |
| DST | Los Angeles Rams DST | 16.00 |
| Total | 77.4 | |
| Starters | ||
| Pos | Player | Points |
| QB | Matt Ryan QB | 14.60 |
| RB | C.J. Anderson RB | 6.00 |
| RB | Chris Ivory RB | 0.10 |
| WR | Mike Williams WR | 3.40 |
| WR | J.J. Nelson WR | 2.20 |
| TE | Jimmy Graham TE | 17.70 |
| FLEX | Kenny Golladay WR | 7.40 |
| FLEX | Paul Richardson WR | 4.80 |
| DST | Houston Texans DST | -1.00 |
| Total | 55.2 | |
| Bench | ||
| Pos | Player | Points |
| BN | Philip Rivers QB | 15.30 |
| BN | David Johnson RB | 0.00 |
| BN | Terrance West RB | 0.00 |
| BN | Devontae Booker RB | 8.80 |
| BN | Odell Beckham WR | 0.00 |
| BN | Donte Moncrief WR | 12.50 |
| BN | Willie Snead WR | 0.00 |
| BN | Travis Kelce TE | 0.00 |
| BN | Philadelphia Eagles DST | 0.00 |
| BN | Jay Cutler QB | 14.40 |
| Bench | ||
| Pos | Player | Points |
| BN | Matthew Stafford QB | 21.70 |
| BN | Leonard Fournette RB | 5.60 |
| BN | DeAndre Hopkins WR | 14.60 |
| BN | Marqise Lee WR | 16.50 |
| BN | Rob Gronkowski TE | 9.40 |
| BN | Devin Funchess TE | 23.70 |
| BN | Duke Johnson RB | 11.80 |
| BN | Julio Jones WR | 8.70 |
| BN | Patrick Mahomes QB | 0.00 |
| BN | Curtis Samuel WR | 9.40 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Ben Roethlisberger QB | 17.90 | 100% |
| RB | Theo Riddick RB | 12.20 | 71.2% |
| RB | Carlos Hyde RB | 11.40 | |
| WR | Donte Moncrief WR | 12.50 | 42.4% |
| WR | Tyler Lockett WR | 5.90 | |
| TE | Jordan Matthews TE | 1.90 | 78.9% |
| FLEX | Devontae Booker RB | 8.80 | 122.5% |
| FLEX | Jordan Howard RB | 5.40 | |
| DST | Los Angeles Rams DST | 16.00 | 100% |
| Total | 92 | 84.1% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Matthew Stafford QB | 21.70 | 67.3% |
| RB | Duke Johnson RB | 11.80 | 34.3% |
| RB | C.J. Anderson RB | 6.00 | |
| WR | Marqise Lee WR | 16.50 | 18% |
| WR | DeAndre Hopkins WR | 14.60 | |
| TE | Devin Funchess TE | 23.70 | 74.7% |
| FLEX | Jimmy Graham TE | 17.70 | 45% |
| FLEX | Rob Gronkowski TE | 9.40 | |
| DST | Houston Texans DST | -1.00 | -- |
| Total | 120.4 | 45.8% | |