| Starters | ||
| Pos | Player | Points |
| QB | Russell Wilson QB | 23.58 |
| RB | Cordarrelle Patterson RB | 17.40 |
| RB | Travis Etienne RB | 21.50 |
| WR | Robert Woods WR | 12.40 |
| WR | Hollywood Brown WR | 9.10 |
| WR | Justin Jefferson WR | 2.00 |
| TE | Hunter Henry TE | 7.70 |
| FLEX | David Montgomery RB | 4.60 |
| FLEX | Tee Higgins WR | 0.00 |
| DST | Green Bay Packers DST | 23.00 |
| Total | 121.28 | |
| Starters | ||
| Pos | Player | Points |
| QB | Mac Jones QB | 20.26 |
| RB | Josh Jacobs RB | 17.50 |
| RB | Kene Nwangwu RB | 7.05 |
| WR | D.K. Metcalf WR | 0.80 |
| WR | Donovan Peoples-Jones WR | 7.80 |
| WR | Brandon Aiyuk WR | 22.20 |
| TE | T.J. Hockenson TE | 9.40 |
| FLEX | Diontae Johnson WR | 4.50 |
| FLEX | CeeDee Lamb WR | 15.50 |
| DST | Tennessee Titans DST | 6.00 |
| Total | 111.01 | |
| Bench | ||
| Pos | Player | Points |
| BN | San Francisco 49ers DST | -3.00 |
| BN | Braxton Berrios WR | 5.85 |
| BN | Jonathan Taylor RB | 0.00 |
| BN | Pat Freiermuth TE | 5.10 |
| BN | DeVonta Smith WR | 16.00 |
| BN | Justin Fields QB | 16.20 |
| Bench | ||
| Pos | Player | Points |
| BN | Mark Ingram RB | 0.00 |
| BN | Minnesota Vikings DST | 0.00 |
| BN | Alec Pierce WR | 3.00 |
| BN | Pierre Strong RB | 1.05 |
| BN | Zamir White RB | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Russell Wilson QB | 23.58 | 100% |
| RB | Travis Etienne RB | 21.50 | 100% |
| RB | Cordarrelle Patterson RB | 17.40 | |
| WR | DeVonta Smith WR | 16.00 | 82.7% |
| WR | Robert Woods WR | 12.40 | |
| TE | Hunter Henry TE | 7.70 | 100% |
| FLEX | Hollywood Brown WR | 9.10 | 29.3% |
| FLEX | DJ Chark Jr. WR | 6.60 | |
| DST | Green Bay Packers DST | 23.00 | 100% |
| Total | 137.28 | 88.3% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Mac Jones QB | 20.26 | 100% |
| RB | Josh Jacobs RB | 17.50 | 100% |
| RB | Kene Nwangwu RB | 7.05 | |
| WR | Brandon Aiyuk WR | 22.20 | 81.7% |
| WR | CeeDee Lamb WR | 15.50 | |
| TE | T.J. Hockenson TE | 9.40 | 100% |
| FLEX | Donovan Peoples-Jones WR | 7.80 | 142.9% |
| FLEX | Chris Olave WR | 6.20 | |
| DST | Tennessee Titans DST | 6.00 | 100% |
| Total | 111.91 | 99.2% | |