| Starters | ||
| Pos | Player | Points |
| QB | Patrick Mahomes QB | 28.32 |
| RB | Devin Singletary RB | 16.30 |
| RB | Najee Harris RB | 13.50 |
| WR | Tyreek Hill WR | 2.90 |
| WR | Chase Claypool WR | 6.10 |
| TE | Zach Ertz TE | 9.40 |
| FLEX | Jarvis Landry WR | 7.50 |
| FLEX | Mike Davis RB | 4.00 |
| DST | Baltimore Ravens DST | -7.00 |
| Total | 81.02 | |
| Starters | ||
| Pos | Player | Points |
| QB | Joe Burrow QB | 46.10 |
| RB | Myles Gaskin RB | 2.10 |
| RB | A.J. Dillon RB | 7.10 |
| WR | Darnell Mooney WR | 8.40 |
| WR | Van Jefferson WR | 1.10 |
| TE | Noah Fant TE | 4.50 |
| FLEX | Damien Harris RB | 28.30 |
| FLEX | Jaylen Waddle WR | 20.20 |
| DST | Dallas Cowboys DST | 26.00 |
| Total | 143.8 | |
| Bench | ||
| Pos | Player | Points |
| BN | Chicago Bears DST | 2.00 |
| BN | Derek Carr QB | 8.54 |
| BN | Austin Hooper TE | 4.10 |
| BN | Matt Breida RB | 0.00 |
| BN | J.D. McKissic RB | 0.00 |
| BN | Anthony Miller WR | 0.00 |
| BN | Justice Hill RB | 0.00 |
| BN | Henry Ruggs III WR | 0.00 |
| BN | Rashod Bateman WR | 10.60 |
| Bench | ||
| Pos | Player | Points |
| BN | Philadelphia Eagles DST | 18.00 |
| BN | Michael Thomas WR | 0.00 |
| BN | Corey Davis WR | 0.00 |
| BN | Carolina Panthers DST | -2.00 |
| BN | Darren Waller TE | 0.00 |
| BN | Ty Johnson RB | 0.00 |
| BN | Trevor Lawrence QB | 12.90 |
| BN | Josh Palmer WR | 12.80 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Patrick Mahomes QB | 28.32 | 100% |
| RB | Devin Singletary RB | 16.30 | 100% |
| RB | Najee Harris RB | 13.50 | |
| WR | Rashod Bateman WR | 10.60 | 49.7% |
| WR | Jarvis Landry WR | 7.50 | |
| TE | Zach Ertz TE | 9.40 | 100% |
| FLEX | Chase Claypool WR | 6.10 | 112.7% |
| FLEX | Austin Hooper TE | 4.10 | |
| DST | Chicago Bears DST | 2.00 | -350% |
| Total | 97.82 | 82.8% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Joe Burrow QB | 46.10 | 100% |
| RB | Damien Harris RB | 28.30 | 26% |
| RB | A.J. Dillon RB | 7.10 | |
| WR | Jaylen Waddle WR | 20.20 | 28.8% |
| WR | Josh Palmer WR | 12.80 | |
| TE | Noah Fant TE | 4.50 | 100% |
| FLEX | Darnell Mooney WR | 8.40 | 461.9% |
| FLEX | Myles Gaskin RB | 2.10 | |
| DST | Dallas Cowboys DST | 26.00 | 100% |
| Total | 155.5 | 92.5% | |