| Starters | ||
| Pos | Player | Points |
| QB | Justin Herbert QB | 26.20 |
| RB | Dalvin Cook RB | -0.30 |
| RB | DAndre Swift RB | 25.60 |
| WR | Tyler Boyd WR | 8.20 |
| WR | JuJu Smith-Schuster WR | 5.30 |
| WR | Jerry Jeudy WR | 4.00 |
| TE | Kyle Pitts TE | 2.50 |
| FLEX | Rachaad White RB | 18.80 |
| FLEX | Breece Hall RB | 0.90 |
| DST | New York Jets DST | -1.00 |
| Total | 90.2 | |
| Starters | ||
| Pos | Player | Points |
| QB | Justin Fields QB | 12.74 |
| RB | Travis Etienne RB | 5.20 |
| RB | Deon Jackson RB | 0.00 |
| WR | Hollywood Brown WR | 14.40 |
| WR | Tee Higgins WR | 24.90 |
| WR | Justin Jefferson WR | 19.40 |
| TE | Pat Freiermuth TE | 0.70 |
| FLEX | Jamaal Williams RB | 2.90 |
| FLEX | DeVonta Smith WR | 21.10 |
| DST | San Francisco 49ers DST | 4.00 |
| Total | 105.34 | |
| Bench | ||
| Pos | Player | Points |
| BN | Kenyan Drake RB | 0.00 |
| BN | Brandin Cooks WR | 0.00 |
| BN | Tyler Conklin TE | 7.50 |
| BN | Desmond Ridder QB | 21.38 |
| BN | David Bell WR | 4.20 |
| BN | Isaiah Spiller RB | 0.30 |
| Bench | ||
| Pos | Player | Points |
| BN | Pittsburgh Steelers DST | 23.00 |
| BN | Dak Prescott QB | 23.60 |
| BN | Jerick McKinnon RB | 3.70 |
| BN | DJ Chark Jr. WR | 2.00 |
| BN | Marquez Valdes-Scantling WR | 2.30 |
| BN | Dawson Knox TE | 8.50 |
| BN | Jonathan Taylor RB | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Justin Herbert QB | 26.20 | 100% |
| RB | DAndre Swift RB | 25.60 | 57% |
| RB | Rachaad White RB | 18.80 | |
| WR | Tyler Boyd WR | 8.20 | 111.5% |
| WR | Mack Hollins WR | 7.50 | |
| TE | Tyler Conklin TE | 7.50 | 33.3% |
| FLEX | JuJu Smith-Schuster WR | 5.30 | 207.4% |
| FLEX | David Bell WR | 4.20 | |
| DST | New York Jets DST | -1.00 | -- |
| Total | 102.3 | 88.2% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Dak Prescott QB | 23.60 | 54% |
| RB | Travis Etienne RB | 5.20 | 58.4% |
| RB | Jerick McKinnon RB | 3.70 | |
| WR | Tee Higgins WR | 24.90 | 127.6% |
| WR | DeVonta Smith WR | 21.10 | |
| TE | Dawson Knox TE | 8.50 | 8.2% |
| FLEX | Justin Jefferson WR | 19.40 | 71% |
| FLEX | Hollywood Brown WR | 14.40 | |
| DST | Pittsburgh Steelers DST | 23.00 | 17.4% |
| Total | 143.8 | 73.3% | |