| Starters | ||
| Pos | Player | Points |
| QB | Josh Allen QB | 21.32 |
| RB | Christian McCaffrey RB | 20.40 |
| RB | Raheem Mostert RB | 41.70 |
| WR | Mike Evans WR | 14.50 |
| WR | Chris Godwin WR | 6.70 |
| WR | Gabriel Davis WR | 9.80 |
| TE | Dalton Schultz TE | 1.40 |
| FLEX | Allen Lazard WR | 5.40 |
| FLEX | Antonio Gibson RB | 4.15 |
| DST | Washington Commanders DST | 0.00 |
| Total | 125.37 | |
| Starters | ||
| Pos | Player | Points |
| QB | Jalen Hurts QB | 17.88 |
| RB | Gus Edwards RB | 5.10 |
| RB | Miles Sanders RB | 14.70 |
| WR | Calvin Ridley WR | 5.50 |
| WR | Braxton Berrios WR | 5.80 |
| WR | Michael Pittman Jr. WR | 12.20 |
| TE | Mark Andrews TE | 5.50 |
| FLEX | Kenneth Gainwell RB | 5.30 |
| FLEX | Sam LaPorta TE | 18.40 |
| DST | New Orleans Saints DST | 9.00 |
| Total | 99.38 | |
| Bench | ||
| Pos | Player | Points |
| BN | Cincinnati Bengals DST | 13.00 |
| BN | DOnta Foreman RB | 0.00 |
| BN | Curtis Samuel WR | 6.40 |
| BN | K.J. Osborn WR | 10.10 |
| BN | Juwan Johnson TE | 2.20 |
| BN | Josh Palmer WR | 12.60 |
| BN | Elijah Mitchell RB | 5.90 |
| BN | Calvin Austin WR | 14.45 |
| BN | Michael Wilson WR | 9.60 |
| Bench | ||
| Pos | Player | Points |
| BN | Detroit Lions DST | 16.00 |
| BN | Ezekiel Elliott RB | 9.20 |
| BN | Buffalo Bills DST | 31.00 |
| BN | David Njoku TE | 4.00 |
| BN | Jeff Wilson Jr. RB | 0.00 |
| BN | Van Jefferson WR | 5.50 |
| BN | Brock Purdy QB | 24.30 |
| BN | Justyn Ross WR | 0.00 |
| BN | Deuce Vaughn RB | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Josh Allen QB | 21.32 | 100% |
| RB | Raheem Mostert RB | 41.70 | 100% |
| RB | Christian McCaffrey RB | 20.40 | |
| WR | Mike Evans WR | 14.50 | 107.1% |
| WR | Calvin Austin WR | 14.45 | |
| TE | Juwan Johnson TE | 2.20 | 63.6% |
| FLEX | Josh Palmer WR | 12.60 | 42.1% |
| FLEX | K.J. Osborn WR | 10.10 | |
| DST | Cincinnati Bengals DST | 13.00 | 0% |
| Total | 150.27 | 83.4% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Brock Purdy QB | 24.30 | 73.6% |
| RB | Miles Sanders RB | 14.70 | 82.8% |
| RB | Ezekiel Elliott RB | 9.20 | |
| WR | Michael Pittman Jr. WR | 12.20 | 115.2% |
| WR | Jordan Addison WR | 8.20 | |
| TE | Sam LaPorta TE | 18.40 | 29.9% |
| FLEX | Braxton Berrios WR | 5.80 | 209.7% |
| FLEX | Mark Andrews TE | 5.50 | |
| DST | Buffalo Bills DST | 31.00 | 29% |
| Total | 129.3 | 76.9% | |