| Starters | ||
| Pos | Player | Points |
| QB | Josh Allen QB | 44.50 |
| RB | Christian McCaffrey RB | 45.20 |
| RB | Raheem Mostert RB | 4.00 |
| WR | Mike Evans WR | 5.50 |
| WR | Chris Godwin WR | 15.40 |
| WR | Gabriel Davis WR | 13.60 |
| TE | Dalton Schultz TE | 11.70 |
| FLEX | Josh Palmer WR | 9.20 |
| FLEX | Calvin Austin WR | 4.85 |
| DST | Cincinnati Bengals DST | 2.00 |
| Total | 155.95 | |
| Starters | ||
| Pos | Player | Points |
| QB | Justin Fields QB | 33.90 |
| RB | Jerick McKinnon RB | 0.70 |
| RB | Travis Etienne RB | 8.70 |
| WR | Hollywood Brown WR | 13.10 |
| WR | Tee Higgins WR | 2.90 |
| WR | Justin Jefferson WR | 23.50 |
| TE | Pat Freiermuth TE | 2.20 |
| FLEX | DJ Chark Jr. WR | 3.80 |
| FLEX | DeVonta Smith WR | 11.30 |
| DST | San Francisco 49ers DST | 1.00 |
| Total | 101.1 | |
| Bench | ||
| Pos | Player | Points |
| BN | Washington Commanders DST | -1.00 |
| BN | DOnta Foreman RB | 0.00 |
| BN | Curtis Samuel WR | 14.70 |
| BN | Allen Lazard WR | 13.60 |
| BN | K.J. Osborn WR | 2.10 |
| BN | Juwan Johnson TE | 0.00 |
| BN | Antonio Gibson RB | 4.55 |
| BN | Elijah Mitchell RB | 0.00 |
| BN | Michael Wilson WR | 23.10 |
| Bench | ||
| Pos | Player | Points |
| BN | Pittsburgh Steelers DST | -6.00 |
| BN | Dak Prescott QB | 16.34 |
| BN | Jamaal Williams RB | 0.00 |
| BN | Marquez Valdes-Scantling WR | 1.10 |
| BN | Dawson Knox TE | 1.70 |
| BN | Craig Reynolds RB | 1.40 |
| BN | Jonathan Taylor RB | 0.00 |
| BN | Deon Jackson RB | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Josh Allen QB | 44.50 | 100% |
| RB | Christian McCaffrey RB | 45.20 | 92.3% |
| RB | Tyjae Spears RB | 8.10 | |
| WR | Michael Wilson WR | 23.10 | 89.6% |
| WR | Chris Godwin WR | 15.40 | |
| TE | Dalton Schultz TE | 11.70 | 100% |
| FLEX | Curtis Samuel WR | 14.70 | 49.6% |
| FLEX | Allen Lazard WR | 13.60 | |
| DST | Cincinnati Bengals DST | 2.00 | 100% |
| Total | 178.3 | 87.5% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Justin Fields QB | 33.90 | 100% |
| RB | Travis Etienne RB | 8.70 | 79.7% |
| RB | Michael Carter RB | 3.10 | |
| WR | Justin Jefferson WR | 23.50 | 107.9% |
| WR | Hollywood Brown WR | 13.10 | |
| TE | Pat Freiermuth TE | 2.20 | 100% |
| FLEX | DeVonta Smith WR | 11.30 | 100% |
| FLEX | DJ Chark Jr. WR | 3.80 | |
| DST | San Francisco 49ers DST | 1.00 | 100% |
| Total | 100.6 | 100.5% | |