| Starters | ||
| Pos | Player | Points |
| QB | Joe Burrow QB | 15.80 |
| RB | Tony Pollard RB | 14.00 |
| RB | David Montgomery RB | 3.80 |
| WR | Stefon Diggs WR | 15.00 |
| WR | Jaylen Waddle WR | 14.60 |
| WR | Puka Nacua WR | 4.60 |
| TE | Evan Engram TE | 7.60 |
| FLEX | Tyler Lockett WR | 12.40 |
| FLEX | James Cook RB | 7.10 |
| DST | Atlanta Falcons DST | 8.00 |
| Total | 102.9 | |
| Starters | ||
| Pos | Player | Points |
| QB | Josh Allen QB | 15.86 |
| RB | Christian McCaffrey RB | 12.70 |
| RB | Raheem Mostert RB | 32.70 |
| WR | Mike Evans WR | 6.90 |
| WR | Chris Godwin WR | 10.70 |
| WR | Gabriel Davis WR | 1.60 |
| TE | Dalton Schultz TE | 14.10 |
| FLEX | DOnta Foreman RB | 7.20 |
| FLEX | K.J. Osborn WR | 6.80 |
| DST | Washington Commanders DST | 7.00 |
| Total | 115.56 | |
| Bench | ||
| Pos | Player | Points |
| BN | Dallas Cowboys DST | 6.00 |
| BN | Matthew Stafford QB | 15.24 |
| BN | Darren Waller TE | 6.80 |
| BN | Justice Hill RB | 5.00 |
| BN | Alexander Mattison RB | 9.20 |
| BN | Zack Moss RB | 14.90 |
| BN | Chuba Hubbard RB | 15.50 |
| BN | Jake Ferguson TE | 2.00 |
| BN | Sam Howell QB | 24.34 |
| BN | Jaleel McLaughlin RB | 5.20 |
| Bench | ||
| Pos | Player | Points |
| BN | Cincinnati Bengals DST | 10.00 |
| BN | Curtis Samuel WR | 12.20 |
| BN | Logan Thomas TE | 0.70 |
| BN | Allen Lazard WR | 1.30 |
| BN | Juwan Johnson TE | 0.00 |
| BN | Antonio Gibson RB | 8.75 |
| BN | Josh Palmer WR | 8.00 |
| BN | Elijah Mitchell RB | -0.30 |
| BN | Calvin Austin WR | 0.00 |
| BN | Michael Wilson WR | 7.70 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Sam Howell QB | 24.34 | 64.9% |
| RB | Chuba Hubbard RB | 15.50 | 58.6% |
| RB | Zack Moss RB | 14.90 | |
| WR | Stefon Diggs WR | 15.00 | 115.5% |
| WR | Jaylen Waddle WR | 14.60 | |
| TE | Evan Engram TE | 7.60 | 100% |
| FLEX | Tony Pollard RB | 14.00 | 73.9% |
| FLEX | Tyler Lockett WR | 12.40 | |
| DST | Atlanta Falcons DST | 8.00 | 100% |
| Total | 126.34 | 81.4% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Josh Allen QB | 15.86 | 100% |
| RB | Raheem Mostert RB | 32.70 | 100% |
| RB | Christian McCaffrey RB | 12.70 | |
| WR | Curtis Samuel WR | 12.20 | 83.8% |
| WR | Chris Godwin WR | 10.70 | |
| TE | Dalton Schultz TE | 14.10 | 100% |
| FLEX | Antonio Gibson RB | 8.75 | 83.6% |
| FLEX | Josh Palmer WR | 8.00 | |
| DST | Cincinnati Bengals DST | 10.00 | 70% |
| Total | 125.01 | 92.4% | |