| Starters | ||
| Pos | Player | Points |
| QB | Patrick Mahomes QB | 1.64 |
| RB | Latavius Murray RB | 1.60 |
| RB | A.J. Dillon RB | 7.70 |
| WR | Drake London WR | 8.00 |
| WR | Jahan Dotson WR | 20.80 |
| WR | Tyquan Thornton WR | 0.00 |
| TE | Travis Kelce TE | 8.80 |
| FLEX | Joe Mixon RB | 18.50 |
| FLEX | Najee Harris RB | 8.00 |
| DST | Miami Dolphins DST | 8.00 |
| Total | 83.04 | |
| Starters | ||
| Pos | Player | Points |
| QB | Russell Wilson QB | 23.56 |
| RB | Derrick Henry RB | 14.20 |
| RB | Austin Ekeler RB | 19.80 |
| WR | Tyreek Hill WR | 21.20 |
| WR | Jakobi Meyers WR | 2.40 |
| WR | Amon-Ra St. Brown WR | 13.80 |
| TE | Dallas Goedert TE | 5.60 |
| FLEX | DeAndre Hopkins WR | 32.80 |
| FLEX | Brandon Powell WR | 3.40 |
| DST | Seattle Seahawks DST | 8.00 |
| Total | 144.76 | |
| Bench | ||
| Pos | Player | Points |
| BN | Denver Broncos DST | 18.00 |
| BN | Derek Carr QB | 22.30 |
| BN | Mike Gesicki TE | 2.10 |
| BN | Devin Singletary RB | 5.30 |
| BN | Chase Claypool WR | 2.00 |
| BN | Clyde Edwards-Helaire RB | 0.40 |
| BN | Jacob Harris WR | 0.00 |
| BN | Jalen Tolbert WR | 0.00 |
| BN | Kyren Williams RB | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Tampa Bay Buccaneers DST | 1.00 |
| BN | Geno Smith QB | 13.86 |
| BN | Taysom Hill TE | 21.96 |
| BN | Joshua Kelley RB | 2.10 |
| BN | Rico Dowdle RB | 3.90 |
| BN | Cam Akers RB | 9.00 |
| BN | Skyy Moore WR | 1.30 |
| BN | Brian Robinson RB | 8.90 |
| BN | Jonathan Mingo WR | 8.20 |
| BN | Kendre Miller RB | 2.40 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Derek Carr QB | 22.30 | 7.4% |
| RB | Joe Mixon RB | 18.50 | 35.1% |
| RB | Najee Harris RB | 8.00 | |
| WR | Jahan Dotson WR | 20.80 | 100% |
| WR | Drake London WR | 8.00 | |
| TE | Travis Kelce TE | 8.80 | 100% |
| FLEX | A.J. Dillon RB | 7.70 | 203.8% |
| FLEX | Devin Singletary RB | 5.30 | |
| DST | Denver Broncos DST | 18.00 | 44.4% |
| Total | 117.4 | 70.7% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Russell Wilson QB | 23.56 | 100% |
| RB | Austin Ekeler RB | 19.80 | 100% |
| RB | Derrick Henry RB | 14.20 | |
| WR | DeAndre Hopkins WR | 32.80 | 69.3% |
| WR | Tyreek Hill WR | 21.20 | |
| TE | Taysom Hill TE | 21.96 | 25.5% |
| FLEX | Amon-Ra St. Brown WR | 13.80 | 158.8% |
| FLEX | Cam Akers RB | 9.00 | |
| DST | Seattle Seahawks DST | 8.00 | 100% |
| Total | 164.32 | 88.1% | |