| Starters | ||
| Pos | Player | Points |
| QB | Justin Herbert QB | 7.14 |
| RB | DAndre Swift RB | 8.40 |
| RB | Rachaad White RB | 25.90 |
| WR | Tyler Boyd WR | 7.10 |
| WR | Brandin Cooks WR | 1.20 |
| WR | JuJu Smith-Schuster WR | 8.10 |
| TE | Kyle Pitts TE | 7.60 |
| FLEX | Tyler Conklin TE | 9.60 |
| FLEX | Breece Hall RB | 8.00 |
| DST | Los Angeles Rams DST | 7.00 |
| Total | 90.04 | |
| Starters | ||
| Pos | Player | Points |
| QB | Lamar Jackson QB | 11.48 |
| RB | Alvin Kamara RB | 9.00 |
| RB | Darrell Henderson RB | 4.50 |
| WR | Cooper Kupp WR | 5.80 |
| WR | D.J. Moore WR | 3.90 |
| WR | Terry McLaurin WR | 9.80 |
| TE | Mark Andrews TE | 12.50 |
| FLEX | Amari Cooper WR | 22.40 |
| FLEX | JaMarr Chase WR | 6.10 |
| DST | New Orleans Saints DST | 12.00 |
| Total | 97.48 | |
| Bench | ||
| Pos | Player | Points |
| BN | Kenyan Drake RB | 0.00 |
| BN | New York Jets DST | 8.00 |
| BN | Dalvin Cook RB | 1.30 |
| BN | Matt Breida RB | 1.60 |
| BN | Jerry Jeudy WR | 0.00 |
| BN | Desmond Ridder QB | 0.00 |
| BN | David Bell WR | 0.00 |
| BN | Isaiah Spiller RB | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Jacksonville Jaguars DST | 0.00 |
| BN | Hunter Henry TE | 11.90 |
| BN | Deshaun Watson QB | 22.96 |
| BN | Gerald Everett TE | 2.80 |
| BN | Michael Gallup WR | 2.90 |
| BN | Kadarius Toney WR | 2.30 |
| BN | Javonte Williams RB | 0.00 |
| BN | Jahmyr Gibbs RB | 0.00 |
| BN | Roschon Johnson RB | 2.00 |
| BN | Zach Evans RB | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Justin Herbert QB | 7.14 | 100% |
| RB | Rachaad White RB | 25.90 | 100% |
| RB | DAndre Swift RB | 8.40 | |
| WR | JuJu Smith-Schuster WR | 8.10 | 107.9% |
| WR | Tyler Boyd WR | 7.10 | |
| TE | Tyler Conklin TE | 9.60 | 79.2% |
| FLEX | Breece Hall RB | 8.00 | 112.8% |
| FLEX | Kyle Pitts TE | 7.60 | |
| DST | New York Jets DST | 8.00 | 87.5% |
| Total | 89.84 | 100.2% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Deshaun Watson QB | 22.96 | 50% |
| RB | Keaton Mitchell RB | 19.90 | 46.7% |
| RB | Alvin Kamara RB | 9.00 | |
| WR | Amari Cooper WR | 22.40 | 60.6% |
| WR | Terry McLaurin WR | 9.80 | |
| TE | Luke Musgrave TE | 12.60 | 99.2% |
| FLEX | Mark Andrews TE | 12.50 | 116.8% |
| FLEX | Hunter Henry TE | 11.90 | |
| DST | New Orleans Saints DST | 12.00 | 100% |
| Total | 133.06 | 73.3% | |