| Starters | ||
| Pos | Player | Points |
| QB | Jake Browning QB | 28.16 |
| RB | Christian McCaffrey RB | 20.80 |
| RB | Raheem Mostert RB | 11.60 |
| WR | Mike Evans WR | 25.70 |
| WR | Curtis Samuel WR | 8.50 |
| WR | Chris Godwin WR | 7.90 |
| TE | Logan Thomas TE | 2.00 |
| FLEX | Allen Lazard WR | 0.00 |
| FLEX | Antonio Gibson RB | 9.20 |
| DST | Kansas City Chiefs DST | 1.00 |
| Total | 114.86 | |
| Starters | ||
| Pos | Player | Points |
| QB | Jalen Hurts QB | 25.92 |
| RB | Miles Sanders RB | 3.40 |
| RB | Zach Charbonnet RB | 16.40 |
| WR | Calvin Ridley WR | 5.30 |
| WR | Michael Pittman Jr. WR | 22.00 |
| WR | Nico Collins WR | 29.60 |
| TE | Sam LaPorta TE | 24.50 |
| FLEX | David Njoku TE | 2.70 |
| FLEX | Trey McBride TE | 18.90 |
| DST | Detroit Lions DST | 4.00 |
| Total | 152.72 | |
| Bench | ||
| Pos | Player | Points |
| BN | New York Giants DST | 0.00 |
| BN | Cincinnati Bengals DST | 2.00 |
| BN | Aaron Jones RB | 0.00 |
| BN | Josh Allen QB | 0.00 |
| BN | Dalton Schultz TE | 0.00 |
| BN | Alexander Mattison RB | 0.00 |
| BN | Gabriel Davis WR | 0.00 |
| BN | Calvin Austin WR | 2.05 |
| BN | Ty Chandler RB | 0.00 |
| BN | Michael Wilson WR | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Buffalo Bills DST | 0.00 |
| BN | Braxton Berrios WR | 0.35 |
| BN | Jeff Wilson Jr. RB | 1.10 |
| BN | Kenneth Gainwell RB | 7.20 |
| BN | Brock Purdy QB | 37.46 |
| BN | Justyn Ross WR | 0.00 |
| BN | Deuce Vaughn RB | 0.00 |
| BN | Emari Demercado RB | 0.00 |
| BN | Jake Bobo WR | 1.40 |
| BN | Keaton Mitchell RB | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Jake Browning QB | 28.16 | 100% |
| RB | Christian McCaffrey RB | 20.80 | 100% |
| RB | Raheem Mostert RB | 11.60 | |
| WR | Mike Evans WR | 25.70 | 123.1% |
| WR | Curtis Samuel WR | 8.50 | |
| TE | Logan Thomas TE | 2.00 | 100% |
| FLEX | Antonio Gibson RB | 9.20 | 53.8% |
| FLEX | Chris Godwin WR | 7.90 | |
| DST | Cincinnati Bengals DST | 2.00 | 50% |
| Total | 115.86 | 99.1% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Brock Purdy QB | 37.46 | 69.2% |
| RB | Zach Charbonnet RB | 16.40 | 83.9% |
| RB | Kenneth Gainwell RB | 7.20 | |
| WR | Nico Collins WR | 29.60 | 110.3% |
| WR | Michael Pittman Jr. WR | 22.00 | |
| TE | Sam LaPorta TE | 24.50 | 100% |
| FLEX | Trey McBride TE | 18.90 | 75.5% |
| FLEX | Jaxon Smith-Njigba WR | 9.70 | |
| DST | Detroit Lions DST | 4.00 | 100% |
| Total | 169.76 | 90% | |