| Starters | ||
| Pos | Player | Points |
| QB | Justin Herbert QB | -0.16 |
| RB | DAndre Swift RB | 3.90 |
| RB | Breece Hall RB | 22.60 |
| WR | Tyler Boyd WR | 3.30 |
| WR | Brandin Cooks WR | 4.70 |
| WR | Jerry Jeudy WR | 2.60 |
| TE | Kyle Pitts TE | 13.20 |
| FLEX | Dalvin Cook RB | 1.30 |
| FLEX | Rachaad White RB | 20.50 |
| DST | Los Angeles Rams DST | 0.00 |
| Total | 71.94 | |
| Starters | ||
| Pos | Player | Points |
| QB | Tua Tagovailoa QB | 9.10 |
| RB | Joe Mixon RB | 20.00 |
| RB | Josh Jacobs RB | 6.00 |
| WR | D.K. Metcalf WR | 12.20 |
| WR | CeeDee Lamb WR | 16.10 |
| WR | Brandon Aiyuk WR | 13.60 |
| TE | T.J. Hockenson TE | 7.80 |
| FLEX | Travis Kelce TE | 11.30 |
| FLEX | Chris Olave WR | 10.80 |
| DST | Green Bay Packers DST | 3.00 |
| Total | 109.9 | |
| Bench | ||
| Pos | Player | Points |
| BN | Kenyan Drake RB | 0.00 |
| BN | New York Jets DST | 12.00 |
| BN | JuJu Smith-Schuster WR | 11.00 |
| BN | Matt Breida RB | 1.60 |
| BN | Tyler Conklin TE | 7.70 |
| BN | Desmond Ridder QB | 25.38 |
| BN | David Bell WR | 10.60 |
| BN | Isaiah Spiller RB | 1.90 |
| Bench | ||
| Pos | Player | Points |
| BN | Philadelphia Eagles DST | 9.00 |
| BN | James Conner RB | 0.00 |
| BN | Diontae Johnson WR | 13.20 |
| BN | Donovan Peoples-Jones WR | 2.20 |
| BN | Trevor Lawrence QB | 17.38 |
| BN | Alec Pierce WR | 3.20 |
| BN | Chig Okonkwo TE | 7.10 |
| BN | Zamir White RB | 0.80 |
| BN | Jerome Ford RB | 10.70 |
| BN | Jaylen Warren RB | 6.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Desmond Ridder QB | 25.38 | -0.6% |
| RB | Breece Hall RB | 22.60 | 61.5% |
| RB | Rachaad White RB | 20.50 | |
| WR | JuJu Smith-Schuster WR | 11.00 | 49.1% |
| WR | David Bell WR | 10.60 | |
| TE | Kyle Pitts TE | 13.20 | 100% |
| FLEX | Tyler Conklin TE | 7.70 | 175.8% |
| FLEX | Brandin Cooks WR | 4.70 | |
| DST | New York Jets DST | 12.00 | 0% |
| Total | 127.68 | 56.3% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Trevor Lawrence QB | 17.38 | 52.4% |
| RB | Joe Mixon RB | 20.00 | 84.7% |
| RB | Jerome Ford RB | 10.70 | |
| WR | CeeDee Lamb WR | 16.10 | 141.1% |
| WR | Brandon Aiyuk WR | 13.60 | |
| TE | Travis Kelce TE | 11.30 | 69% |
| FLEX | Diontae Johnson WR | 13.20 | 87% |
| FLEX | D.K. Metcalf WR | 12.20 | |
| DST | Philadelphia Eagles DST | 9.00 | 33.3% |
| Total | 123.48 | 89% | |