| Starters | ||
| Pos | Player | Points |
| RB | Aaron Jones RB | 0.00 |
| RB | Storm Johnson RB | 0.00 |
| WR | Marvin Jones WR | 25.90 |
| WR | Julian Edelman WR | 0.00 |
| TE | Fred Davis TE | 0.00 |
| FLEX | Clark Harris TE | 0.00 |
| FLEX | Brian Hill RB | 0.00 |
| DST | Tampa Bay Buccaneers DST | -5.00 |
| Total | 20.9 | |
| Starters | ||
| Pos | Player | Points |
| QB | Chad Kelly QB | 0.00 |
| RB | Ty Montgomery RB | 0.00 |
| RB | Jeremy McNichols RB | 0.00 |
| WR | Golden Tate WR | 4.70 |
| WR | Cameron Meredith WR | 0.00 |
| TE | George Kittle TE | 1.90 |
| FLEX | Tyler Boyd WR | 8.70 |
| FLEX | Jonathan Williams RB | 0.00 |
| DST | Kansas City Chiefs DST | 5.00 |
| Total | 20.3 | |
| Bench | ||
| Pos | Player | Points |
| BN | Alfred Blue RB | 0.00 |
| BN | Christian McCaffrey RB | 11.80 |
| BN | DeMarco Murray RB | 11.70 |
| BN | Jay Ajayi RB | 3.80 |
| BN | Brandin Cooks WR | 18.40 |
| BN | Emmanuel Sanders WR | 2.70 |
| BN | Zach Ertz TE | 21.30 |
| BN | Baltimore Ravens DST | 9.00 |
| BN | Adam Shaheen TE | 0.60 |
| BN | T.Y. Hilton WR | 2.50 |
| BN | Davante Adams WR | 16.70 |
| Bench | ||
| Pos | Player | Points |
| BN | Kirk Cousins QB | 16.10 |
| BN | Samaje Perine RB | 14.50 |
| BN | Frank Gore RB | 14.90 |
| BN | Bilal Powell RB | 5.10 |
| BN | Jarvis Landry WR | 11.00 |
| BN | Taylor Gabriel WR | 3.10 |
| BN | DeSean Jackson WR | 10.00 |
| BN | Alex Smith QB | 13.50 |
| BN | Detroit Lions DST | 2.00 |
| BN | Tyler Kroft TE | 8.90 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| RB | Christian McCaffrey RB | 11.80 | 0% |
| RB | DeMarco Murray RB | 11.70 | |
| WR | Marvin Jones WR | 25.90 | 58.5% |
| WR | Brandin Cooks WR | 18.40 | |
| TE | Zach Ertz TE | 21.30 | 0% |
| FLEX | Davante Adams WR | 16.70 | 0% |
| FLEX | Jay Ajayi RB | 3.80 | |
| DST | Baltimore Ravens DST | 9.00 | -55.6% |
| Total | 118.6 | 17.6% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Kirk Cousins QB | 16.10 | 0% |
| RB | Frank Gore RB | 14.90 | 0% |
| RB | Samaje Perine RB | 14.50 | |
| WR | Jarvis Landry WR | 11.00 | 22.4% |
| WR | DeSean Jackson WR | 10.00 | |
| TE | Tyler Kroft TE | 8.90 | 21.3% |
| FLEX | Tyler Boyd WR | 8.70 | 63% |
| FLEX | Bilal Powell RB | 5.10 | |
| DST | Kansas City Chiefs DST | 5.00 | 100% |
| Total | 94.2 | 21.5% | |