| Starters | ||
| Pos | Player | Points |
| QB | Josh Allen QB | 38.92 |
| RB | Antonio Gibson RB | 5.20 |
| RB | Ty Chandler RB | 1.30 |
| WR | Allen Lazard WR | 12.30 |
| WR | Gabriel Davis WR | 2.80 |
| WR | Michael Wilson WR | 10.40 |
| TE | Dallas Goedert TE | 22.00 |
| FLEX | Tucker Kraft TE | 3.40 |
| FLEX | Dontayvion Wicks WR | 0.00 |
| DST | Kansas City Chiefs DST | 5.00 |
| Total | 101.32 | |
| Starters | ||
| Pos | Player | Points |
| QB | C.J. Stroud QB | 7.80 |
| RB | James Conner RB | 3.00 |
| RB | Saquon Barkley RB | 31.60 |
| WR | Courtland Sutton WR | 10.30 |
| WR | George Pickens WR | 8.20 |
| WR | Tank Dell WR | 8.70 |
| TE | George Kittle TE | 0.00 |
| FLEX | DOnta Foreman RB | 0.50 |
| FLEX | Alexander Mattison RB | 11.90 |
| DST | New York Jets DST | 16.00 |
| Total | 98 | |
| Bench | ||
| Pos | Player | Points |
| BN | Curtis Samuel WR | 3.70 |
| BN | Logan Thomas TE | 0.00 |
| BN | Kenneth Gainwell RB | 4.75 |
| BN | Jordan Addison WR | 0.00 |
| BN | Evan Hull RB | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Keenan Allen WR | 0.00 |
| BN | Baltimore Ravens DST | 2.00 |
| BN | Jamaal Williams RB | 0.40 |
| BN | Kareem Hunt RB | 0.00 |
| BN | A.J. Brown WR | 0.00 |
| BN | Jordan Love QB | 0.00 |
| BN | Romeo Doubs WR | 2.30 |
| BN | Javon Baker WR | 0.00 |
| BN | Jaylen Wright RB | 1.70 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Josh Allen QB | 38.92 | 100% |
| RB | Antonio Gibson RB | 5.20 | 65.3% |
| RB | Kenneth Gainwell RB | 4.75 | |
| WR | Allen Lazard WR | 12.30 | 112.3% |
| WR | Michael Wilson WR | 10.40 | |
| TE | Dallas Goedert TE | 22.00 | 100% |
| FLEX | Brock Bowers TE | 5.60 | 36.6% |
| FLEX | Curtis Samuel WR | 3.70 | |
| DST | Kansas City Chiefs DST | 5.00 | 100% |
| Total | 107.87 | 93.9% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | C.J. Stroud QB | 7.80 | 100% |
| RB | Saquon Barkley RB | 31.60 | 79.5% |
| RB | Alexander Mattison RB | 11.90 | |
| WR | Courtland Sutton WR | 10.30 | 143.2% |
| WR | Tank Dell WR | 8.70 | |
| TE | Theo Johnson TE | 1.80 | 0% |
| FLEX | George Pickens WR | 8.20 | 80% |
| FLEX | Brian Thomas WR | 7.30 | |
| DST | New York Jets DST | 16.00 | 100% |
| Total | 103.6 | 94.6% | |