| Starters | ||
| Pos | Player | Points |
| QB | Jalen Hurts QB | 24.76 |
| RB | J.K. Dobbins RB | 8.10 |
| RB | Chuba Hubbard RB | 11.20 |
| WR | Jaxon Smith-Njigba WR | 3.80 |
| WR | Ladd McConkey WR | 7.10 |
| WR | Jordan Whittington WR | 0.00 |
| TE | Trey McBride TE | 7.60 |
| FLEX | Nick Chubb RB | 9.70 |
| FLEX | Sam LaPorta TE | 3.00 |
| DST | Detroit Lions DST | 5.00 |
| Total | 80.26 | |
| Starters | ||
| Pos | Player | Points |
| QB | Justin Herbert QB | 14.76 |
| RB | Rachaad White RB | 26.10 |
| RB | Breece Hall RB | 23.10 |
| WR | Stefon Diggs WR | 4.80 |
| WR | JuJu Smith-Schuster WR | 0.00 |
| WR | Jerry Jeudy WR | 2.30 |
| TE | Kyle Pitts TE | 10.00 |
| FLEX | Rashod Bateman WR | 20.10 |
| FLEX | Tyler Allgeier RB | 5.00 |
| DST | Los Angeles Rams DST | 17.00 |
| Total | 123.16 | |
| Bench | ||
| Pos | Player | Points |
| BN | Seattle Seahawks DST | 15.00 |
| BN | Tennessee Titans DST | -1.00 |
| BN | Calvin Ridley WR | 5.70 |
| BN | Michael Pittman Jr. WR | 7.80 |
| BN | Josh Palmer WR | 8.30 |
| BN | Nico Collins WR | 0.00 |
| BN | Brock Purdy QB | 11.18 |
| BN | Zach Charbonnet RB | 1.40 |
| BN | Keaton Mitchell RB | 0.00 |
| BN | Luke McCaffrey WR | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Michael Thomas WR | 0.00 |
| BN | New England Patriots DST | -2.00 |
| BN | Kansas City Chiefs DST | 7.00 |
| BN | Deshaun Watson QB | 5.12 |
| BN | DAndre Swift RB | 0.00 |
| BN | K.J. Osborn WR | 9.60 |
| BN | Kadarius Toney WR | 0.00 |
| BN | Khalil Herbert RB | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Jalen Hurts QB | 24.76 | 100% |
| RB | Chuba Hubbard RB | 11.20 | 92.3% |
| RB | Nick Chubb RB | 9.70 | |
| WR | Keon Coleman WR | 14.50 | 47.3% |
| WR | Greg Dortch WR | 8.55 | |
| TE | Trey McBride TE | 7.60 | 100% |
| FLEX | Josh Palmer WR | 8.30 | 77.4% |
| FLEX | J.K. Dobbins RB | 8.10 | |
| DST | Seattle Seahawks DST | 15.00 | 33.3% |
| Total | 107.71 | 74.5% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Justin Herbert QB | 14.76 | 100% |
| RB | Rachaad White RB | 26.10 | 100% |
| RB | Breece Hall RB | 23.10 | |
| WR | Rashod Bateman WR | 20.10 | 23.9% |
| WR | K.J. Osborn WR | 9.60 | |
| TE | Kyle Pitts TE | 10.00 | 100% |
| FLEX | Tyler Allgeier RB | 5.00 | 256.1% |
| FLEX | Stefon Diggs WR | 4.80 | |
| DST | Los Angeles Rams DST | 17.00 | 100% |
| Total | 130.46 | 94.4% | |