| Starters | ||
| Pos | Player | Points |
| QB | Patrick Mahomes QB | 20.18 |
| RB | Najee Harris RB | 14.60 |
| RB | Kyren Williams RB | 20.10 |
| WR | Davante Adams WR | 7.40 |
| WR | Drake London WR | 5.40 |
| WR | Malik Nabers WR | 10.60 |
| TE | Noah Fant TE | 3.70 |
| FLEX | Tyreek Hill WR | 10.20 |
| FLEX | Rhamondre Stevenson RB | 22.00 |
| DST | Denver Broncos DST | 9.00 |
| Total | 123.18 | |
| Starters | ||
| Pos | Player | Points |
| QB | Caleb Williams QB | 9.34 |
| RB | Brian Robinson RB | 8.10 |
| RB | Bucky Irving RB | 11.90 |
| WR | Jakobi Meyers WR | 14.20 |
| WR | Amon-Ra St. Brown WR | 7.70 |
| WR | Khalil Shakir WR | 15.40 |
| TE | Cade Otton TE | 24.60 |
| FLEX | Rico Dowdle RB | 0.00 |
| FLEX | Tyrone Tracy RB | 22.00 |
| DST | Buffalo Bills DST | 10.00 |
| Total | 123.24 | |
| Bench | ||
| Pos | Player | Points |
| BN | Miami Dolphins DST | -1.00 |
| BN | Geno Smith QB | 6.08 |
| BN | Gus Edwards RB | 0.00 |
| BN | Devin Singletary RB | 3.30 |
| BN | Clyde Edwards-Helaire RB | 0.00 |
| BN | Jahan Dotson WR | 0.00 |
| BN | Jalen Tolbert WR | 5.90 |
| BN | Michael Mayer TE | 0.00 |
| BN | Ben Sinnott TE | 0.00 |
| BN | Isaiah Davis RB | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | DeAndre Hopkins WR | 3.90 |
| BN | Russell Wilson QB | 15.82 |
| BN | Tampa Bay Buccaneers DST | 2.00 |
| BN | Austin Ekeler RB | 8.00 |
| BN | Daniel Jones QB | 4.66 |
| BN | Cam Akers RB | 0.00 |
| BN | Jonathan Mingo WR | 0.00 |
| BN | Israel Abanikanda RB | 0.00 |
| BN | Xavier Hutchinson WR | 2.40 |
| BN | JaTavion Sanders TE | 1.20 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Patrick Mahomes QB | 20.18 | 100% |
| RB | Rhamondre Stevenson RB | 22.00 | 82.4% |
| RB | Kyren Williams RB | 20.10 | |
| WR | Malik Nabers WR | 10.60 | 112.5% |
| WR | Tyreek Hill WR | 10.20 | |
| TE | Noah Fant TE | 3.70 | 100% |
| FLEX | Najee Harris RB | 14.60 | 146.4% |
| FLEX | Davante Adams WR | 7.40 | |
| DST | Denver Broncos DST | 9.00 | 100% |
| Total | 117.78 | 104.6% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Russell Wilson QB | 15.82 | 59% |
| RB | Tyrone Tracy RB | 22.00 | 59% |
| RB | Bucky Irving RB | 11.90 | |
| WR | Khalil Shakir WR | 15.40 | 126% |
| WR | Jakobi Meyers WR | 14.20 | |
| TE | Cade Otton TE | 24.60 | 100% |
| FLEX | Brian Robinson RB | 8.10 | 136.6% |
| FLEX | Austin Ekeler RB | 8.00 | |
| DST | Buffalo Bills DST | 10.00 | 100% |
| Total | 130.02 | 94.8% | |