| Starters | ||
| Pos | Player | Points |
| QB | Jared Goff QB | 10.76 |
| RB | Aaron Jones RB | 18.40 |
| RB | Josh Jacobs RB | 28.60 |
| WR | Deebo Samuel WR | 5.20 |
| WR | Zay Flowers WR | 8.70 |
| WR | Xavier Worthy WR | 7.10 |
| TE | Zach Ertz TE | 12.80 |
| FLEX | Kenneth Walker RB | 11.30 |
| FLEX | Jayden Reed WR | 5.10 |
| DST | Houston Texans DST | 18.00 |
| Total | 125.96 | |
| Starters | ||
| Pos | Player | Points |
| QB | Baker Mayfield QB | 18.66 |
| RB | Tony Pollard RB | 20.40 |
| RB | David Montgomery RB | 14.80 |
| WR | Jauan Jennings WR | 6.50 |
| WR | Josh Downs WR | 4.40 |
| WR | Puka Nacua WR | 16.20 |
| TE | David Njoku TE | 3.40 |
| FLEX | Jaylen Waddle WR | 24.40 |
| FLEX | Quentin Johnston WR | 0.00 |
| DST | Chicago Bears DST | -1.00 |
| Total | 107.76 | |
| Bench | ||
| Pos | Player | Points |
| BN | Los Angeles Chargers DST | -1.00 |
| BN | Samaje Perine RB | 8.60 |
| BN | Adam Thielen WR | 7.20 |
| BN | Taysom Hill TE | 0.00 |
| BN | Kyler Murray QB | 8.30 |
| BN | Miles Sanders RB | 0.00 |
| BN | Cole Kmet TE | 9.90 |
| BN | Rashid Shaheed WR | 0.00 |
| BN | Kayshon Boutte WR | 1.10 |
| BN | Ray Davis RB | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Philadelphia Eagles DST | 9.00 |
| BN | Evan Engram TE | 0.00 |
| BN | Mike Williams WR | 0.00 |
| BN | Zack Moss RB | 0.00 |
| BN | Joe Burrow QB | 0.00 |
| BN | Travis Etienne RB | 0.00 |
| BN | James Cook RB | 0.00 |
| BN | Jake Ferguson TE | 0.00 |
| BN | Demario Douglas WR | 8.80 |
| BN | Kimani Vidal RB | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Bo Nix QB | 23.42 | 45.9% |
| RB | Josh Jacobs RB | 28.60 | 100% |
| RB | Aaron Jones RB | 18.40 | |
| WR | Zay Flowers WR | 8.70 | 132.1% |
| WR | Adam Thielen WR | 7.20 | |
| TE | Zach Ertz TE | 12.80 | 100% |
| FLEX | Kenneth Walker RB | 11.30 | 77.4% |
| FLEX | Cole Kmet TE | 9.90 | |
| DST | Houston Texans DST | 18.00 | 100% |
| Total | 138.32 | 91.1% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Baker Mayfield QB | 18.66 | 100% |
| RB | Tony Pollard RB | 20.40 | 100% |
| RB | David Montgomery RB | 14.80 | |
| WR | Jaylen Waddle WR | 24.40 | 66.7% |
| WR | Puka Nacua WR | 16.20 | |
| TE | David Njoku TE | 3.40 | 100% |
| FLEX | Demario Douglas WR | 8.80 | 156.9% |
| FLEX | Dameon Pierce RB | 6.75 | |
| DST | Philadelphia Eagles DST | 9.00 | -11.1% |
| Total | 122.41 | 88% | |