| Starters | ||
| Pos | Player | Points |
| QB | Josh Allen QB | 32.42 |
| RB | James Conner RB | 9.60 |
| RB | Joe Mixon RB | 19.90 |
| WR | Mike Evans WR | 21.80 |
| WR | Courtland Sutton WR | 13.20 |
| WR | CeeDee Lamb WR | 4.90 |
| TE | George Kittle TE | 1.20 |
| FLEX | Saquon Barkley RB | 18.70 |
| FLEX | A.J. Brown WR | 9.10 |
| DST | New York Jets DST | 17.00 |
| Total | 147.82 | |
| Starters | ||
| Pos | Player | Points |
| QB | Jordan Love QB | 22.96 |
| RB | Antonio Gibson RB | 16.20 |
| RB | Kenneth Gainwell RB | 1.15 |
| WR | Jordan Addison WR | 7.40 |
| WR | Dontayvion Wicks WR | 5.00 |
| WR | Brian Thomas WR | 16.70 |
| TE | Dallas Goedert TE | 11.00 |
| FLEX | Michael Wilson WR | 8.00 |
| FLEX | Parker Washington WR | 21.30 |
| Total | 109.71 | |
| Bench | ||
| Pos | Player | Points |
| BN | Arizona Cardinals DST | 9.00 |
| BN | Jameis Winston QB | 34.98 |
| BN | Joe Flacco QB | 0.00 |
| BN | Baltimore Ravens DST | 4.00 |
| BN | Jamaal Williams RB | 1.20 |
| BN | Kareem Hunt RB | 2.50 |
| BN | George Pickens WR | 14.90 |
| BN | Romeo Doubs WR | 0.00 |
| BN | Tucker Kraft TE | 10.80 |
| BN | Javon Baker WR | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Curtis Samuel WR | 0.70 |
| BN | Logan Thomas TE | 0.00 |
| BN | Gabriel Davis WR | 0.00 |
| BN | Ty Chandler RB | 0.20 |
| BN | Evan Hull RB | 0.00 |
| BN | Audric Estime RB | 1.20 |
| BN | Jalen Coker WR | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Jameis Winston QB | 34.98 | 92.7% |
| RB | Joe Mixon RB | 19.90 | 76.4% |
| RB | Saquon Barkley RB | 18.70 | |
| WR | Mike Evans WR | 21.80 | 108.7% |
| WR | George Pickens WR | 14.90 | |
| TE | Tucker Kraft TE | 10.80 | 11.1% |
| FLEX | Courtland Sutton WR | 13.20 | 121.9% |
| FLEX | James Conner RB | 9.60 | |
| DST | New York Jets DST | 17.00 | 100% |
| Total | 160.88 | 91.9% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Jordan Love QB | 22.96 | 100% |
| RB | Antonio Gibson RB | 16.20 | 95.3% |
| RB | Trey Benson RB | 2.00 | |
| WR | Parker Washington WR | 21.30 | 76.6% |
| WR | Brian Thomas WR | 16.70 | |
| TE | Brock Bowers TE | 25.20 | 43.7% |
| FLEX | Dallas Goedert TE | 11.00 | 140.2% |
| FLEX | Calvin Austin WR | 9.90 | |
| Total | 125.26 | 87.6% | |