| Starters | ||
| Pos | Player | Points |
| QB | Matthew Stafford QB | 19.62 |
| RB | Derrick Henry RB | 12.60 |
| RB | Jonathan Taylor RB | 16.80 |
| WR | Cooper Kupp WR | 3.20 |
| WR | Tee Higgins WR | 15.40 |
| WR | Justin Jefferson WR | 13.40 |
| TE | Travis Kelce TE | 10.30 |
| FLEX | Christian McCaffrey RB | 7.70 |
| FLEX | Jonnu Smith TE | 16.30 |
| DST | Dallas Cowboys DST | 18.00 |
| Total | 133.32 | |
| Starters | ||
| Pos | Player | Points |
| QB | Jared Goff QB | 20.94 |
| RB | Aaron Jones RB | 8.30 |
| RB | Josh Jacobs RB | 19.70 |
| WR | Deebo Samuel WR | 12.40 |
| WR | Zay Flowers WR | 8.60 |
| WR | Xavier Worthy WR | 7.90 |
| TE | Taysom Hill TE | 7.20 |
| FLEX | Kenneth Walker RB | 5.60 |
| FLEX | Jayden Reed WR | 18.20 |
| DST | Houston Texans DST | 1.00 |
| Total | 109.84 | |
| Bench | ||
| Pos | Player | Points |
| BN | Dak Prescott QB | 0.00 |
| BN | Ezekiel Elliott RB | 0.40 |
| BN | Tyler Lockett WR | 3.10 |
| BN | San Francisco 49ers DST | -4.00 |
| BN | Raheem Mostert RB | 4.40 |
| BN | Tua Tagovailoa QB | 29.20 |
| BN | Trevor Lawrence QB | -1.76 |
| BN | Pat Freiermuth TE | 15.80 |
| BN | DeVonta Smith WR | 0.00 |
| BN | Tyjae Spears RB | 1.75 |
| Bench | ||
| Pos | Player | Points |
| BN | Los Angeles Chargers DST | 17.00 |
| BN | Zach Ertz TE | 11.00 |
| BN | Samaje Perine RB | 3.30 |
| BN | Adam Thielen WR | 19.90 |
| BN | Kyler Murray QB | 13.20 |
| BN | Miles Sanders RB | 0.00 |
| BN | Cole Kmet TE | 4.10 |
| BN | Rashid Shaheed WR | 0.00 |
| BN | Kayshon Boutte WR | 7.60 |
| BN | Ray Davis RB | 15.35 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Tua Tagovailoa QB | 29.20 | 67.2% |
| RB | Jonathan Taylor RB | 16.80 | 100% |
| RB | Derrick Henry RB | 12.60 | |
| WR | Tee Higgins WR | 15.40 | 111.1% |
| WR | Justin Jefferson WR | 13.40 | |
| TE | Jonnu Smith TE | 16.30 | 63.2% |
| FLEX | Pat Freiermuth TE | 15.80 | 92% |
| FLEX | Travis Kelce TE | 10.30 | |
| DST | Dallas Cowboys DST | 18.00 | 100% |
| Total | 147.8 | 90.2% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Jared Goff QB | 20.94 | 100% |
| RB | Josh Jacobs RB | 19.70 | 79.9% |
| RB | Ray Davis RB | 15.35 | |
| WR | Adam Thielen WR | 19.90 | 75.9% |
| WR | Jayden Reed WR | 18.20 | |
| TE | Zach Ertz TE | 11.00 | 65.5% |
| FLEX | Deebo Samuel WR | 12.40 | 113.3% |
| FLEX | Zay Flowers WR | 8.60 | |
| DST | Los Angeles Chargers DST | 17.00 | 5.9% |
| Total | 143.09 | 76.8% | |