| Starters | ||
| Pos | Player | Points |
| QB | Anthony Richardson QB | 9.88 |
| RB | Isaih Pacheco RB | 5.20 |
| RB | Tank Bigsby RB | 4.20 |
| WR | Garrett Wilson WR | 13.10 |
| WR | Marvin Mims WR | 8.85 |
| WR | Xavier Legette WR | 1.90 |
| TE | Mark Andrews TE | 9.40 |
| FLEX | Breece Hall RB | 12.10 |
| FLEX | Bijan Robinson RB | 14.00 |
| DST | Indianapolis Colts DST | 10.00 |
| Total | 88.63 | |
| Starters | ||
| Pos | Player | Points |
| QB | Justin Herbert QB | 15.80 |
| RB | Rachaad White RB | 13.10 |
| RB | Tyler Allgeier RB | 4.30 |
| WR | Jerry Jeudy WR | 16.30 |
| WR | Rashod Bateman WR | 21.50 |
| WR | Jameson Williams WR | 11.20 |
| TE | Kyle Pitts TE | 4.80 |
| FLEX | Christian Watson WR | 7.10 |
| FLEX | Zach Charbonnet RB | 13.10 |
| DST | New England Patriots DST | -1.00 |
| Total | 106.2 | |
| Bench | ||
| Pos | Player | Points |
| BN | Kirk Cousins QB | 6.48 |
| BN | Cleveland Browns DST | 0.00 |
| BN | T.J. Hockenson TE | 7.70 |
| BN | WanDale Robinson WR | 5.80 |
| BN | Tre Tucker WR | 2.80 |
| BN | Emanuel Wilson RB | 0.90 |
| BN | Jaylen Wright RB | 0.30 |
| BN | Carson Steele RB | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Brandin Cooks WR | 4.90 |
| BN | Los Angeles Rams DST | 12.00 |
| BN | Deshaun Watson QB | 0.00 |
| BN | JuJu Smith-Schuster WR | 7.20 |
| BN | K.J. Osborn WR | 0.00 |
| BN | Kadarius Toney WR | 0.00 |
| BN | Khalil Herbert RB | 0.40 |
| BN | Roschon Johnson RB | 0.00 |
| BN | Braelon Allen RB | 0.50 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Anthony Richardson QB | 9.88 | 100% |
| RB | Bijan Robinson RB | 14.00 | 36% |
| RB | Breece Hall RB | 12.10 | |
| WR | Garrett Wilson WR | 13.10 | 108.7% |
| WR | Marvin Mims WR | 8.85 | |
| TE | Mark Andrews TE | 9.40 | 100% |
| FLEX | T.J. Hockenson TE | 7.70 | 193.3% |
| FLEX | WanDale Robinson WR | 5.80 | |
| DST | Indianapolis Colts DST | 10.00 | 100% |
| Total | 90.83 | 97.6% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Justin Herbert QB | 15.80 | 100% |
| RB | Zach Charbonnet RB | 13.10 | 66.4% |
| RB | Rachaad White RB | 13.10 | |
| WR | Rashod Bateman WR | 21.50 | 129.6% |
| WR | Jerry Jeudy WR | 16.30 | |
| TE | Kyle Pitts TE | 4.80 | 100% |
| FLEX | Jameson Williams WR | 11.20 | 109.8% |
| FLEX | JuJu Smith-Schuster WR | 7.20 | |
| DST | Los Angeles Rams DST | 12.00 | -8.3% |
| Total | 115 | 92.3% | |