| Starters | ||
| Pos | Player | Points |
| QB | Russell Wilson QB | 14.02 |
| RB | Carlos Hyde RB | 25.00 |
| RB | David Johnson RB | 24.60 |
| WR | Odell Beckham WR | 15.60 |
| WR | Kelvin Benjamin WR | 0.00 |
| TE | Travis Kelce TE | 17.90 |
| FLEX | Jordan Matthews TE | 8.90 |
| FLEX | Willie Snead WR | 0.00 |
| DST | Pittsburgh Steelers DST | -4.00 |
| Total | 102.02 | |
| Starters | ||
| Pos | Player | Points |
| QB | Cam Newton QB | 13.08 |
| RB | Christine Michael RB | 24.10 |
| RB | Darren Sproles RB | 22.50 |
| WR | Will Fuller WR | 4.60 |
| WR | DeAndre Hopkins WR | 7.60 |
| TE | Eric Ebron TE | 9.40 |
| FLEX | Fozzy Whittaker RB | 8.10 |
| FLEX | Julio Jones WR | 2.10 |
| DST | Denver Broncos DST | 9.00 |
| Total | 100.48 | |
| Bench | ||
| Pos | Player | Points |
| BN | Philip Rivers QB | 11.24 |
| BN | Kenyan Drake RB | 5.80 |
| BN | Derrick Henry RB | 4.50 |
| BN | Chris Johnson RB | 0.50 |
| BN | Theo Riddick RB | 8.30 |
| BN | Terrance West RB | 5.80 |
| BN | James White RB | 1.90 |
| BN | Tyler Lockett WR | 3.50 |
| BN | Donte Moncrief WR | 0.00 |
| BN | Philadelphia Eagles DST | 16.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Marcus Mariota QB | 4.76 |
| BN | Kenneth Dixon RB | 0.00 |
| BN | Arian Foster RB | 0.00 |
| BN | Alfred Morris RB | 8.60 |
| BN | T.J. Yeldon RB | 3.80 |
| BN | Josh Gordon WR | 0.00 |
| BN | Jermaine Kearse WR | 2.10 |
| BN | Laquon Treadwell WR | 0.00 |
| BN | Kevin White WR | 9.20 |
| BN | Julius Thomas TE | 2.30 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Russell Wilson QB | 14.02 | 100% |
| RB | Carlos Hyde RB | 25.00 | 100% |
| RB | David Johnson RB | 24.60 | |
| WR | Odell Beckham WR | 15.60 | 81.7% |
| WR | Tyler Lockett WR | 3.50 | |
| TE | Travis Kelce TE | 17.90 | 100% |
| FLEX | Jordan Matthews TE | 8.90 | 51.7% |
| FLEX | Theo Riddick RB | 8.30 | |
| DST | Philadelphia Eagles DST | 16.00 | -25% |
| Total | 133.82 | 76.2% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Cam Newton QB | 13.08 | 100% |
| RB | Christine Michael RB | 24.10 | 100% |
| RB | Darren Sproles RB | 22.50 | |
| WR | Kevin White WR | 9.20 | 72.6% |
| WR | DeAndre Hopkins WR | 7.60 | |
| TE | Eric Ebron TE | 9.40 | 100% |
| FLEX | Alfred Morris RB | 8.60 | 61.1% |
| FLEX | Fozzy Whittaker RB | 8.10 | |
| DST | Denver Broncos DST | 9.00 | 100% |
| Total | 111.58 | 90.1% | |