| Starters | ||
| Pos | Player | Points |
| QB | Josh Allen QB | 30.82 |
| RB | Samaje Perine RB | 3.65 |
| RB | Bam Knight RB | 5.70 |
| WR | Kendrick Bourne WR | 4.40 |
| WR | George Pickens WR | 10.90 |
| WR | Calvin Austin WR | 8.10 |
| TE | Theo Johnson TE | 10.20 |
| FLEX | Christian Kirk WR | 4.60 |
| FLEX | Darius Slayton WR | 8.70 |
| DST | Kansas City Chiefs DST | -1.00 |
| Total | 86.07 | |
| Starters | ||
| Pos | Player | Points |
| QB | Bo Nix QB | 20.52 |
| RB | Kenneth Walker RB | 7.10 |
| RB | RJ Harvey RB | 16.80 |
| WR | D.J. Moore WR | 22.98 |
| WR | Rashid Shaheed WR | 11.20 |
| WR | Kayshon Boutte WR | 0.00 |
| TE | Zach Ertz TE | 6.60 |
| FLEX | Zay Flowers WR | 8.90 |
| FLEX | Xavier Worthy WR | 4.50 |
| DST | Los Angeles Chargers DST | 9.00 |
| Total | 107.6 | |
| Bench | ||
| Pos | Player | Points |
| BN | Minnesota Vikings DST | 9.00 |
| BN | New York Jets DST | 0.00 |
| BN | James Conner RB | 0.00 |
| BN | Mack Hollins WR | 1.90 |
| BN | Saquon Barkley RB | 0.00 |
| BN | A.J. Brown WR | 0.00 |
| BN | Tua Tagovailoa QB | 6.54 |
| BN | Brenton Strange TE | 0.00 |
| BN | Sean Tucker RB | 0.00 |
| BN | Devin Neal RB | 1.70 |
| Bench | ||
| Pos | Player | Points |
| BN | Aaron Rodgers QB | 14.12 |
| BN | San Francisco 49ers DST | 4.00 |
| BN | Jared Goff QB | 23.36 |
| BN | Aaron Jones RB | 10.80 |
| BN | Taysom Hill TE | 3.00 |
| BN | Jayden Reed WR | 0.00 |
| BN | Jaleel McLaughlin RB | 0.00 |
| BN | Ray Davis RB | 5.25 |
| BN | Terrance Ferguson TE | 6.40 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Josh Allen QB | 30.82 | 100% |
| RB | Emari Demercado RB | 8.30 | 66.8% |
| RB | Bam Knight RB | 5.70 | |
| WR | George Pickens WR | 10.90 | 119.4% |
| WR | Darius Slayton WR | 8.70 | |
| TE | Theo Johnson TE | 10.20 | 100% |
| FLEX | Calvin Austin WR | 8.10 | 104.7% |
| FLEX | Christian Kirk WR | 4.60 | |
| DST | Minnesota Vikings DST | 9.00 | -11.1% |
| Total | 96.32 | 89.4% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Jared Goff QB | 23.36 | 87.8% |
| RB | RJ Harvey RB | 16.80 | 86.6% |
| RB | Aaron Jones RB | 10.80 | |
| WR | D.J. Moore WR | 22.98 | 100% |
| WR | Rashid Shaheed WR | 11.20 | |
| TE | Zach Ertz TE | 6.60 | 100% |
| FLEX | Zay Flowers WR | 8.90 | 83.8% |
| FLEX | Kenneth Walker RB | 7.10 | |
| DST | Los Angeles Chargers DST | 9.00 | 100% |
| Total | 116.74 | 92.2% | |