| Starters | ||
| Pos | Player | Points |
| QB | Justin Herbert QB | 29.70 |
| RB | Rachaad White RB | 0.00 |
| RB | Kyren Williams RB | 17.40 |
| WR | DeVonta Smith WR | 0.00 |
| WR | Jameson Williams WR | 14.60 |
| WR | Tetairoa McMillan WR | 6.60 |
| TE | Kyle Pitts TE | 5.80 |
| FLEX | Stefon Diggs WR | 11.30 |
| FLEX | Zach Charbonnet RB | 5.10 |
| DST | New England Patriots DST | 3.00 |
| Total | 93.5 | |
| Starters | ||
| Pos | Player | Points |
| QB | Jaxson Dart QB | 31.24 |
| RB | Kimani Vidal RB | 3.00 |
| RB | Kyle Monangai RB | 21.30 |
| WR | Tee Higgins WR | 29.60 |
| WR | Michael Pittman Jr. WR | 16.00 |
| WR | Jordan Addison WR | 7.40 |
| TE | Dallas Goedert TE | 0.00 |
| FLEX | Kenneth Gainwell RB | 5.40 |
| FLEX | Romeo Doubs WR | 12.90 |
| Total | 126.84 | |
| Bench | ||
| Pos | Player | Points |
| BN | JuJu Smith-Schuster WR | 0.70 |
| BN | K.J. Osborn WR | 0.00 |
| BN | Cole Kmet TE | 1.50 |
| BN | Rashod Bateman WR | 8.30 |
| BN | Khalil Herbert RB | 0.00 |
| BN | Christian Watson WR | 6.80 |
| BN | Tank Dell WR | 0.00 |
| BN | Roschon Johnson RB | 0.00 |
| BN | Braelon Allen RB | 0.00 |
| BN | Colston Loveland TE | 26.80 |
| Bench | ||
| Pos | Player | Points |
| BN | Tre Tucker WR | 5.30 |
| BN | Dontayvion Wicks WR | 0.00 |
| BN | Parker Washington WR | 13.20 |
| BN | Keaton Mitchell RB | 3.50 |
| BN | Brian Thomas WR | 7.00 |
| BN | Jalen Coker WR | 1.40 |
| BN | Jarquez Hunter RB | 0.00 |
| BN | Tory Horton WR | 18.80 |
| BN | DJ Giddens RB | 0.00 |
| BN | KeAndre Lambert-Smith WR | 2.45 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Justin Herbert QB | 29.70 | 100% |
| RB | Kyren Williams RB | 17.40 | 77.3% |
| RB | Zach Charbonnet RB | 5.10 | |
| WR | Jameson Williams WR | 14.60 | 81.9% |
| WR | Stefon Diggs WR | 11.30 | |
| TE | Colston Loveland TE | 26.80 | 21.6% |
| FLEX | Rashod Bateman WR | 8.30 | 108.6% |
| FLEX | Christian Watson WR | 6.80 | |
| DST | New England Patriots DST | 3.00 | 100% |
| Total | 123 | 76% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Jaxson Dart QB | 31.24 | 100% |
| RB | Kyle Monangai RB | 21.30 | 62.8% |
| RB | Ashton Jeanty RB | 17.40 | |
| WR | Tee Higgins WR | 29.60 | 109.5% |
| WR | Tory Horton WR | 18.80 | |
| TE | Brock Bowers TE | 37.30 | 0% |
| FLEX | Michael Pittman Jr. WR | 16.00 | 62.7% |
| FLEX | Parker Washington WR | 13.20 | |
| Total | 184.84 | 68.6% | |