| Starters | ||
| Pos | Player | Points |
| QB | Jalen Hurts QB | 14.50 |
| RB | DAndre Swift RB | 9.00 |
| RB | Breece Hall RB | 7.40 |
| WR | Nico Collins WR | 19.70 |
| WR | Jaxon Smith-Njigba WR | 16.10 |
| WR | Ladd McConkey WR | 2.80 |
| TE | Trey McBride TE | 22.50 |
| FLEX | Chuba Hubbard RB | 5.85 |
| FLEX | Jordan Whittington WR | 3.80 |
| DST | Detroit Lions DST | 4.00 |
| Total | 105.65 | |
| Starters | ||
| Pos | Player | Points |
| QB | Trevor Lawrence QB | 15.02 |
| RB | Jaylen Warren RB | 7.70 |
| RB | Chris Rodriguez RB | 9.00 |
| WR | D.K. Metcalf WR | 7.40 |
| WR | Malik Washington WR | 6.90 |
| WR | Jaylin Noel WR | 6.15 |
| TE | Oronde Gadsden TE | 5.10 |
| FLEX | Kareem Hunt RB | 12.70 |
| FLEX | George Kittle TE | 21.70 |
| DST | Green Bay Packers DST | 6.00 |
| Total | 97.67 | |
| Bench | ||
| Pos | Player | Points |
| BN | Los Angeles Rams DST | 5.00 |
| BN | Sam Darnold QB | -3.74 |
| BN | J.K. Dobbins RB | 0.00 |
| BN | Michael Carter RB | 6.65 |
| BN | Brock Purdy QB | 25.30 |
| BN | Josh Downs WR | 0.00 |
| BN | Sam LaPorta TE | 0.00 |
| BN | Keon Coleman WR | 0.00 |
| BN | MarShawn Lloyd RB | 0.00 |
| BN | Luke McCaffrey WR | 0.00 |
| BN | Isaac Guerendo RB | 0.00 |
| Bench | ||
| Pos | Player | Points |
| BN | Justice Hill RB | 0.00 |
| BN | Brandon Aiyuk WR | 0.00 |
| BN | Chris Olave WR | 0.00 |
| BN | Alec Pierce WR | 0.00 |
| BN | Jerome Ford RB | 0.20 |
| BN | C.J. Stroud QB | 0.00 |
| BN | Mason Taylor TE | 5.00 |
| BN | Kyle Williams WR | 0.00 |
| BN | Dylan Sampson RB | 4.30 |
| BN | Jalen Royals WR | 0.00 |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Brock Purdy QB | 25.30 | 57.3% |
| RB | DAndre Swift RB | 9.00 | 100% |
| RB | Breece Hall RB | 7.40 | |
| WR | Nico Collins WR | 19.70 | 107.8% |
| WR | Jaxon Smith-Njigba WR | 16.10 | |
| TE | Trey McBride TE | 22.50 | 100% |
| FLEX | Michael Carter RB | 6.65 | 74.2% |
| FLEX | LeQuint Allen RB | 6.35 | |
| DST | Los Angeles Rams DST | 5.00 | 80% |
| Total | 118 | 89.5% | |
| Potential Lineup | |||
| Pos | Player | Points | Eff % |
| QB | Drake Maye QB | 17.44 | 86.1% |
| RB | Kareem Hunt RB | 12.70 | 77% |
| RB | Chris Rodriguez RB | 9.00 | |
| WR | D.K. Metcalf WR | 7.40 | 143% |
| WR | Malik Washington WR | 6.90 | |
| TE | George Kittle TE | 21.70 | 23.5% |
| FLEX | Jaylen Warren RB | 7.70 | 248.4% |
| FLEX | Jaylin Noel WR | 6.15 | |
| DST | Green Bay Packers DST | 6.00 | 100% |
| Total | 94.99 | 102.8% | |